BDBM50442606 CHEMBL2441430

SMILES: [O-][N+](=O)c1ccc(CCN2CCN(CC2)C(=O)Cc2ccc(cc2)[N+]([O-])=O)cc1

InChI Key: InChIKey=HKQOYSCGJPIZFG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50442606   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ATP-sensitive inward rectifier potassium channel 1 (Homo sapiens (Human))	BDBM50442606 (CHEMBL2441430) Show SMILES [O-][N+](=O)c1ccc(CCN2CCN(CC2)C(=O)Cc2ccc(cc2)[N+]([O-])=O)cc1 Show InChI InChI=1S/C20H22N4O5/c25-20(15-17-3-7-19(8-4-17)24(28)29)22-13-11-21(12-14-22)10-9-16-1-5-18(6-2-16)23(26)27/h1-8H,9-15H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human ROMK channel-mediated 86Rb+ flux expressed in CHO cells after 35 mins by scintillation counting analysis				Bioorg Med Chem Lett 23: 5829-32 (2013) Article DOI: 10.1016/j.bmcl.2013.08.104 BindingDB Entry DOI: 10.7270/Q28K7BHG
					More data for this Ligand-Target Pair