BDBM50442814 CHEMBL2440745

SMILES: CCCOC(=O)c1cccc(c1)-c1cc(ccc1CN)C(=O)Nc1ccncc1

InChI Key: InChIKey=OVIAEPAPINRQRA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50442814   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50442814 (CHEMBL2440745) Show SMILES CCCOC(=O)c1cccc(c1)-c1cc(ccc1CN)C(=O)Nc1ccncc1 Show InChI InChI=1S/C23H23N3O3/c1-2-12-29-23(28)18-5-3-4-16(13-18)21-14-17(6-7-19(21)15-24)22(27)26-20-8-10-25-11-9-20/h3-11,13-14H,2,12,15,24H2,1H3,(H,25,26,27)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Amakem N.V. Curated by ChEMBL					Assay Description Inhibition of ROCK2 (unknown origin) using long S6 kinase peptide as substrate by radiometric assay				Bioorg Med Chem Lett 23: 6442-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.040 BindingDB Entry DOI: 10.7270/Q2BC411W
					More data for this Ligand-Target Pair