BDBM50442828 CHEMBL2440740

SMILES: NCc1ccc(cc1-c1cccc(c1)C(O)=O)C(=O)Nc1ccncc1F

InChI Key: InChIKey=IGQRXPNMALPSCN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50442828   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50442828 (CHEMBL2440740) Show SMILES NCc1ccc(cc1-c1cccc(c1)C(O)=O)C(=O)Nc1ccncc1F Show InChI InChI=1S/C20H16FN3O3/c21-17-11-23-7-6-18(17)24-19(25)13-4-5-15(10-22)16(9-13)12-2-1-3-14(8-12)20(26)27/h1-9,11H,10,22H2,(H,26,27)(H,23,24,25)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
Amakem N.V. Curated by ChEMBL					Assay Description Inhibition of ROCK2 (unknown origin) using long S6 kinase peptide as substrate by radiometric assay				Bioorg Med Chem Lett 23: 6442-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.040 BindingDB Entry DOI: 10.7270/Q2BC411W
					More data for this Ligand-Target Pair