BDBM50442936 CHEMBL3087166
SMILES: B[P@@](=O)(OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)OP(O)(=O)C(Cl)(Cl)P(O)(O)=O
InChI Key: InChIKey=JAINGMDYZCRCHP-PFLBIVCZSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 (Homo sapiens (Human)) | BDBM50442936 (CHEMBL3087166) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Université Laval Curated by ChEMBL | Assay Description Mixed type inhibition of human NPP1 expressed in COS7 cells assessed as production of p-nitrophenol using pnp-TMP as the substrate preincubated for 3... | J Med Chem 56: 8308-20 (2013) Article DOI: 10.1021/jm400918s BindingDB Entry DOI: 10.7270/Q2F47QMF | |||||||||||
More data for this Ligand-Target Pair |