BDBM50443582 CHEMBL3091989

SMILES: CS(=O)(=O)NC1C[C@@H]2CCCC[C@@H]2[C@H]1\C=C\c1ccc(cn1)-c1cccc(F)c1

InChI Key: InChIKey=WORVMFGYOZJSID-DGRVINJVSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50443582   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proteinase-activated receptor 1 (Homo sapiens (Human))	BDBM50443582 (CHEMBL3091989) Show SMILES CS(=O)(=O)NC1C[C@@H]2CCCC[C@@H]2[C@H]1\C=C\c1ccc(cn1)-c1cccc(F)c1 |r| Show InChI InChI=1S/C23H27FN2O2S/c1-29(27,28)26-23-14-17-5-2-3-8-21(17)22(23)12-11-20-10-9-18(15-25-20)16-6-4-7-19(24)13-16/h4,6-7,9-13,15,17,21-23,26H,2-3,5,8,14H2,1H3/b12-11+/t17-,21-,22+,23?/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Technology Curated by ChEMBL					Assay Description Antagonist activity at PAR1 in human platelet rich plasma assessed as inhibition of haTRAP-induced platelet aggregation preincubated for 1 hr followe...				ACS Med Chem Lett 4: 1054-8 (2013) Article DOI: 10.1021/ml400235c BindingDB Entry DOI: 10.7270/Q2KH0PSN
					More data for this Ligand-Target Pair
Proteinase-activated receptor 1 (Homo sapiens (Human))	BDBM50443582 (CHEMBL3091989) Show SMILES CS(=O)(=O)NC1C[C@@H]2CCCC[C@@H]2[C@H]1\C=C\c1ccc(cn1)-c1cccc(F)c1 |r| Show InChI InChI=1S/C23H27FN2O2S/c1-29(27,28)26-23-14-17-5-2-3-8-21(17)22(23)12-11-20-10-9-18(15-25-20)16-6-4-7-19(24)13-16/h4,6-7,9-13,15,17,21-23,26H,2-3,5,8,14H2,1H3/b12-11+/t17-,21-,22+,23?/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Technology Curated by ChEMBL					Assay Description Displacement of [3H]haTRAP from PAR1 in human platelet membranes after 60 mins by scintillation counting analysis				ACS Med Chem Lett 4: 1054-8 (2013) Article DOI: 10.1021/ml400235c BindingDB Entry DOI: 10.7270/Q2KH0PSN
					More data for this Ligand-Target Pair
Proteinase-activated receptor 1 (Homo sapiens (Human))	BDBM50443582 (CHEMBL3091989) Show SMILES CS(=O)(=O)NC1C[C@@H]2CCCC[C@@H]2[C@H]1\C=C\c1ccc(cn1)-c1cccc(F)c1 |r| Show InChI InChI=1S/C23H27FN2O2S/c1-29(27,28)26-23-14-17-5-2-3-8-21(17)22(23)12-11-20-10-9-18(15-25-20)16-6-4-7-19(24)13-16/h4,6-7,9-13,15,17,21-23,26H,2-3,5,8,14H2,1H3/b12-11+/t17-,21-,22+,23?/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Technology Curated by ChEMBL					Assay Description Antagonist activity at PAR1 in washed human platelets assessed as inhibition of haTRAP-induced platelet aggregation preincubated for 1 hr followed by...				ACS Med Chem Lett 4: 1054-8 (2013) Article DOI: 10.1021/ml400235c BindingDB Entry DOI: 10.7270/Q2KH0PSN
					More data for this Ligand-Target Pair