BDBM50443598 CHEMBL3091979

SMILES: CC(=O)NC1C[C@@H]2CCCC[C@@H]2[C@H]1\C=C\c1ccc(cn1)-c1cccc(F)c1

InChI Key: InChIKey=FPNKXRVENVIZHG-HMWKPFPJSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50443598   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proteinase-activated receptor 1 (Homo sapiens (Human))	BDBM50443598 (CHEMBL3091979) Show SMILES CC(=O)NC1C[C@@H]2CCCC[C@@H]2[C@H]1\C=C\c1ccc(cn1)-c1cccc(F)c1 |r| Show InChI InChI=1S/C24H27FN2O/c1-16(28)27-24-14-18-5-2-3-8-22(18)23(24)12-11-21-10-9-19(15-26-21)17-6-4-7-20(25)13-17/h4,6-7,9-13,15,18,22-24H,2-3,5,8,14H2,1H3,(H,27,28)/b12-11+/t18-,22-,23+,24?/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Technology Curated by ChEMBL					Assay Description Displacement of [3H]haTRAP from PAR1 in human platelet membranes after 60 mins by scintillation counting analysis				ACS Med Chem Lett 4: 1054-8 (2013) Article DOI: 10.1021/ml400235c BindingDB Entry DOI: 10.7270/Q2KH0PSN
					More data for this Ligand-Target Pair