BDBM50443661 CHEMBL3093063

SMILES: Fc1ccccc1CNc1nnc(o1)-c1c[nH]c2ncccc12

InChI Key: InChIKey=XSETWWGSORWVMB-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50443661   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
CDC7 and DBF4 (Homo sapiens (Human))	BDBM50443661 (CHEMBL3093063) Show SMILES Fc1ccccc1CNc1nnc(o1)-c1c[nH]c2ncccc12 Show InChI InChI=1S/C16H12FN5O/c17-13-6-2-1-4-10(13)8-20-16-22-21-15(23-16)12-9-19-14-11(12)5-3-7-18-14/h1-7,9H,8H2,(H,18,19)(H,20,22)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of Cdc7/Dbf4 (unknown origin)-mediated MCM2 phosphorylation at Ser53 by protein A amplified luminescent proximity homogeneous assay				Bioorg Med Chem Lett 23: 6396-400 (2013) Article DOI: 10.1016/j.bmcl.2013.09.055 BindingDB Entry DOI: 10.7270/Q2P84DC0
					More data for this Ligand-Target Pair
Cell division cycle 7-related protein kinase (Homo sapiens (Human))	BDBM50443661 (CHEMBL3093063) Show SMILES Fc1ccccc1CNc1nnc(o1)-c1c[nH]c2ncccc12 Show InChI InChI=1S/C16H12FN5O/c17-13-6-2-1-4-10(13)8-20-16-22-21-15(23-16)12-9-19-14-11(12)5-3-7-18-14/h1-7,9H,8H2,(H,18,19)(H,20,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of Cdc7-mediated MCM2 phosphorylation at Ser53 in human HCT116 cells after 14 hrs by immunostaining assay				Bioorg Med Chem Lett 23: 6396-400 (2013) Article DOI: 10.1016/j.bmcl.2013.09.055 BindingDB Entry DOI: 10.7270/Q2P84DC0
					More data for this Ligand-Target Pair
CDK2/CycE (Homo sapiens (Human))	BDBM50443661 (CHEMBL3093063) Show SMILES Fc1ccccc1CNc1nnc(o1)-c1c[nH]c2ncccc12 Show InChI InChI=1S/C16H12FN5O/c17-13-6-2-1-4-10(13)8-20-16-22-21-15(23-16)12-9-19-14-11(12)5-3-7-18-14/h1-7,9H,8H2,(H,18,19)(H,20,22)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	580	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of CDK2/cyclin E (unknown origin) using ULight peptide as substrate by HTRF assay				Bioorg Med Chem Lett 23: 6396-400 (2013) Article DOI: 10.1016/j.bmcl.2013.09.055 BindingDB Entry DOI: 10.7270/Q2P84DC0
					More data for this Ligand-Target Pair