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BDBM50443788 CHEMBL3094213

SMILES: CC(C)N1CCC(CC1)Oc1ccc2CCNCCc2c1

InChI Key: InChIKey=XFMAJARUDAULHP-UHFFFAOYSA-N

Data: 1 KI

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50443788   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H1 receptor


(Homo sapiens (Human))
BDBM50443788
PNG
(CHEMBL3094213)
Show SMILES CC(C)N1CCC(CC1)Oc1ccc2CCNCCc2c1
Show InChI InChI=1S/C18H28N2O/c1-14(2)20-11-7-17(8-12-20)21-18-4-3-15-5-9-19-10-6-16(15)13-18/h3-4,13-14,17,19H,5-12H2,1-2H3
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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
>2.51E+3n/an/an/an/an/an/an/an/a



GlaxoSmithKline R&D

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant histamine H1 receptor expressed in CHO cells assessed as inhibition of histamine-induced effect by FLIPR ass...


Bioorg Med Chem Lett 23: 6897-901 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.089
BindingDB Entry DOI: 10.7270/Q2HM59X6
More data for this
Ligand-Target Pair