BDBM50443844 CHEMBL3091506

SMILES: CCc1c(cccc1S(=O)(=O)N[C@@H](CNC(=O)c1ccc(Cl)s1)C(=O)N1CCOCC1)N1CCOCC1=O

InChI Key: InChIKey=QHRDZTQSQGOQEL-KRWDZBQOSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50443844   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50443844 (CHEMBL3091506) Show SMILES CCc1c(cccc1S(=O)(=O)N[C@@H](CNC(=O)c1ccc(Cl)s1)C(=O)N1CCOCC1)N1CCOCC1=O |r| Show InChI InChI=1S/C24H29ClN4O7S2/c1-2-16-18(29-10-13-36-15-22(29)30)4-3-5-20(16)38(33,34)27-17(24(32)28-8-11-35-12-9-28)14-26-23(31)19-6-7-21(25)37-19/h3-7,17,27H,2,8-15H2,1H3,(H,26,31)/t17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi-Aventis R&D Curated by ChEMBL					Assay Description Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assay				J Med Chem 56: 9441-56 (2014) Article DOI: 10.1021/jm4005835 BindingDB Entry DOI: 10.7270/Q20K2B0C
					More data for this Ligand-Target Pair