BDBM50443859 CHEMBL3091504

SMILES: CCc1c(cccc1S(=O)(=O)N[C@@H](Cc1cc(on1)-c1ccc(Cl)s1)C(=O)N1CCC(O)CC1)N1CCOCC1=O

InChI Key: InChIKey=RKLBLCDJBJDJCD-FQEVSTJZSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50443859   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50443859 (CHEMBL3091504) Show SMILES CCc1c(cccc1S(=O)(=O)N[C@@H](Cc1cc(on1)-c1ccc(Cl)s1)C(=O)N1CCC(O)CC1)N1CCOCC1=O |r| Show InChI InChI=1S/C27H31ClN4O7S2/c1-2-19-21(32-12-13-38-16-26(32)34)4-3-5-24(19)41(36,37)30-20(27(35)31-10-8-18(33)9-11-31)14-17-15-22(39-29-17)23-6-7-25(28)40-23/h3-7,15,18,20,30,33H,2,8-14,16H2,1H3/t20-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi-Aventis R&D Curated by ChEMBL					Assay Description Inhibition of human coagulation factor 10a using S-2765 as substrate measured up to 20 mins by chromogenic assay				J Med Chem 56: 9441-56 (2014) Article DOI: 10.1021/jm4005835 BindingDB Entry DOI: 10.7270/Q20K2B0C
					More data for this Ligand-Target Pair