BDBM50443891 CHEMBL3091550

SMILES: Cc1cc(nc(Nc2ccc(cc2)C(=O)Nc2c(C)cccc2C)n1)-c1ccc(OC(F)(F)F)cc1

InChI Key: InChIKey=XTCGGRNUDKFRID-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50443891   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sonic hedgehog protein (Mus musculus (Mouse))	BDBM50443891 (CHEMBL3091550) Show SMILES Cc1cc(nc(Nc2ccc(cc2)C(=O)Nc2c(C)cccc2C)n1)-c1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C27H23F3N4O2/c1-16-5-4-6-17(2)24(16)34-25(35)20-7-11-21(12-8-20)32-26-31-18(3)15-23(33-26)19-9-13-22(14-10-19)36-27(28,29)30/h4-15H,1-3H3,(H,34,35)(H,31,32,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Jiangsu Simcere Pharmaceutical Co. Ltd Curated by ChEMBL					Assay Description Inhibition of SHH signaling pathway in mouse NIH3T3 cells measured after 48 hrs by Gli-luciferase reporter assay				Bioorg Med Chem Lett 23: 6777-83 (2013) Article DOI: 10.1016/j.bmcl.2013.10.022 BindingDB Entry DOI: 10.7270/Q2R49S7W
					More data for this Ligand-Target Pair