BDBM50443934 CHEMBL3091797

SMILES: Nc1ncnc2c1oc1cc(cnc21)-c1ccc(Cl)cc1Cl

InChI Key: InChIKey=DXMSZKBTTLFUPL-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50443934   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-Dependent Kinase 5 (CDK5) (Homo sapiens (Human))	BDBM50443934 (CHEMBL3091797) Show SMILES Nc1ncnc2c1oc1cc(cnc21)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C15H8Cl2N4O/c16-8-1-2-9(10(17)4-8)7-3-11-12(19-5-7)13-14(22-11)15(18)21-6-20-13/h1-6H,(H2,18,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
UMR 6014& FR 3038; Univ Rouen; INSA Rouen; CNRS Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/p25 using [gamma-33P]ATP as substrate after 30 mins by scintillation counting analysis				Bioorg Med Chem Lett 23: 6784-8 (2013) Article DOI: 10.1016/j.bmcl.2013.10.019 BindingDB Entry DOI: 10.7270/Q2MC91HJ
					More data for this Ligand-Target Pair
Dual specificty protein kinase CLK1 (Homo sapiens (Human))	BDBM50443934 (CHEMBL3091797) Show SMILES Nc1ncnc2c1oc1cc(cnc21)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C15H8Cl2N4O/c16-8-1-2-9(10(17)4-8)7-3-11-12(19-5-7)13-14(22-11)15(18)21-6-20-13/h1-6H,(H2,18,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
UMR 6014& FR 3038; Univ Rouen; INSA Rouen; CNRS Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-tagged CLK1 expressed in Escherichia coli using GRSRSRSRSRSR as substrate				Bioorg Med Chem Lett 23: 6784-8 (2013) Article DOI: 10.1016/j.bmcl.2013.10.019 BindingDB Entry DOI: 10.7270/Q2MC91HJ
					More data for this Ligand-Target Pair
Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A (RAT)	BDBM50443934 (CHEMBL3091797) Show SMILES Nc1ncnc2c1oc1cc(cnc21)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C15H8Cl2N4O/c16-8-1-2-9(10(17)4-8)7-3-11-12(19-5-7)13-14(22-11)15(18)21-6-20-13/h1-6H,(H2,18,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
UMR 6014& FR 3038; Univ Rouen; INSA Rouen; CNRS Curated by ChEMBL					Assay Description Inhibition of rat recombinant GST-tagged DYRK1A expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate after 30 mins by scintillation counti...				Bioorg Med Chem Lett 23: 6784-8 (2013) Article DOI: 10.1016/j.bmcl.2013.10.019 BindingDB Entry DOI: 10.7270/Q2MC91HJ
					More data for this Ligand-Target Pair