null

SMILES: OC(=O)c1cc(ccc1N1CC[C@@H](C1)Oc1ccc(F)cc1)C(F)(F)F

InChI Key: InChIKey=CSSXFCMIJIHVOO-AWEZNQCLSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50444144   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatic triacylglycerol lipase (Homo sapiens (Human))	BDBM50444144 (CHEMBL3093302) Show SMILES OC(=O)c1cc(ccc1N1CC[C@@H](C1)Oc1ccc(F)cc1)C(F)(F)F |r| Show InChI InChI=1S/C18H15F4NO3/c19-12-2-4-13(5-3-12)26-14-7-8-23(10-14)16-6-1-11(18(20,21)22)9-15(16)17(24)25/h1-6,9,14H,7-8,10H2,(H,24,25)/t14-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of recombinant human hepatic lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by FEL...				Bioorg Med Chem 21: 7724-34 (2013) Article DOI: 10.1016/j.bmc.2013.10.023 BindingDB Entry DOI: 10.7270/Q2P55PZ8
					More data for this Ligand-Target Pair
Endothelial lipase (Homo sapiens (Human))	BDBM50444144 (CHEMBL3093302) Show SMILES OC(=O)c1cc(ccc1N1CC[C@@H](C1)Oc1ccc(F)cc1)C(F)(F)F |r| Show InChI InChI=1S/C18H15F4NO3/c19-12-2-4-13(5-3-12)26-14-7-8-23(10-14)16-6-1-11(18(20,21)22)9-15(16)17(24)25/h1-6,9,14H,7-8,10H2,(H,24,25)/t14-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	184	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of recombinant human endothelial lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...				Bioorg Med Chem 21: 7724-34 (2013) Article DOI: 10.1016/j.bmc.2013.10.023 BindingDB Entry DOI: 10.7270/Q2P55PZ8
					More data for this Ligand-Target Pair
Lipoprotein lipase (Homo sapiens (Human))	BDBM50444144 (CHEMBL3093302) Show SMILES OC(=O)c1cc(ccc1N1CC[C@@H](C1)Oc1ccc(F)cc1)C(F)(F)F |r| Show InChI InChI=1S/C18H15F4NO3/c19-12-2-4-13(5-3-12)26-14-7-8-23(10-14)16-6-1-11(18(20,21)22)9-15(16)17(24)25/h1-6,9,14H,7-8,10H2,(H,24,25)/t14-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of recombinant human lipoprotein lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...				Bioorg Med Chem 21: 7724-34 (2013) Article DOI: 10.1016/j.bmc.2013.10.023 BindingDB Entry DOI: 10.7270/Q2P55PZ8
					More data for this Ligand-Target Pair