BDBM50444163 CHEMBL3093424

SMILES: NS(=O)(=O)c1ccc(cc1)-c1nsc(NC(=O)N(CCC(c2ccccc2)c2ccccc2)CCN2CCOCC2)n1

InChI Key: InChIKey=CCRIZQAFGGNNSQ-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50444163   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50444163 (CHEMBL3093424) Show SMILES NS(=O)(=O)c1ccc(cc1)-c1nsc(NC(=O)N(CCC(c2ccccc2)c2ccccc2)CCN2CCOCC2)n1 Show InChI InChI=1S/C30H34N6O4S2/c31-42(38,39)26-13-11-25(12-14-26)28-32-29(41-34-28)33-30(37)36(18-17-35-19-21-40-22-20-35)16-15-27(23-7-3-1-4-8-23)24-9-5-2-6-10-24/h1-14,27H,15-22H2,(H2,31,38,39)(H,32,33,34,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Activation of human CaSR				Bioorg Med Chem Lett 23: 6625-8 (2013) Article DOI: 10.1016/j.bmcl.2013.10.050 BindingDB Entry DOI: 10.7270/Q2JD4Z7Z
					More data for this Ligand-Target Pair