BDBM50444164 CHEMBL3093423

SMILES: CS(=O)(=O)Nc1ccc(cc1)-c1nsc(NC(=O)N(CCC(c2ccccc2)c2ccccc2)CCN2CCOCC2)n1

InChI Key: InChIKey=LPXWVCOHAWUFQZ-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50444164   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Extracellular calcium-sensing receptor (Homo sapiens (Human))	BDBM50444164 (CHEMBL3093423) Show SMILES CS(=O)(=O)Nc1ccc(cc1)-c1nsc(NC(=O)N(CCC(c2ccccc2)c2ccccc2)CCN2CCOCC2)n1 Show InChI InChI=1S/C31H36N6O4S2/c1-43(39,40)35-27-14-12-26(13-15-27)29-32-30(42-34-29)33-31(38)37(19-18-36-20-22-41-23-21-36)17-16-28(24-8-4-2-5-9-24)25-10-6-3-7-11-25/h2-15,28,35H,16-23H2,1H3,(H,32,33,34,38)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Activation of human CaSR				Bioorg Med Chem Lett 23: 6625-8 (2013) Article DOI: 10.1016/j.bmcl.2013.10.050 BindingDB Entry DOI: 10.7270/Q2JD4Z7Z
					More data for this Ligand-Target Pair