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SMILES: NS(=O)(=O)c1ccc(cc1)-c1nc(NC(=O)N(CCC(c2ccc(F)cc2)c2ccc(F)cc2)CCN2CCOCC2)sc1Cl

InChI Key: InChIKey=QCDLMADYWHJZRQ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50444171   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Extracellular calcium-sensing receptor


(Homo sapiens (Human))		BDBM50444171
PNG
(CHEMBL3093427)
Show SMILES NS(=O)(=O)c1ccc(cc1)-c1nc(NC(=O)N(CCC(c2ccc(F)cc2)c2ccc(F)cc2)CCN2CCOCC2)sc1Cl
Show InChI InChI=1S/C31H32ClF2N5O4S2/c32-29-28(23-5-11-26(12-6-23)45(35,41)42)36-30(44-29)37-31(40)39(16-15-38-17-19-43-20-18-38)14-13-27(21-1-7-24(33)8-2-21)22-3-9-25(34)10-4-22/h1-12,27H,13-20H2,(H2,35,41,42)(H,36,37,40)
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Similars
Article
PubMed
n/an/an/an/a 10n/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Activation of human CaSR

Bioorg Med Chem Lett 23: 6625-8 (2013)


Article DOI: 10.1016/j.bmcl.2013.10.050
BindingDB Entry DOI: 10.7270/Q2JD4Z7Z
More data for this
Ligand-Target Pair