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BDBM50444412 CHEMBL3091584

SMILES: OC(=O)c1ccc(NC(=O)[C@H](CC2CCOCC2)n2cnc(c2)S(=O)(=O)C2CC2)nc1

InChI Key: InChIKey=KAGKVRONFJTRGB-INIZCTEOSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50444412   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glucokinase/Glucokinase regulatory protein


(Homo sapiens (Human))
BDBM50444412
PNG
(CHEMBL3091584)
Show SMILES OC(=O)c1ccc(NC(=O)[C@H](CC2CCOCC2)n2cnc(c2)S(=O)(=O)C2CC2)nc1 |r|
Show InChI InChI=1S/C20H24N4O6S/c25-19(23-17-4-1-14(10-21-17)20(26)27)16(9-13-5-7-30-8-6-13)24-11-18(22-12-24)31(28,29)15-2-3-15/h1,4,10-13,15-16H,2-3,5-9H2,(H,26,27)(H,21,23,25)/t16-/m0/s1
PDB
MMDB

NCI pathway
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KEGG

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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 1.35E+3n/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Activation of recombinant human glucokinase by G6PDH/NADP coupled assay


Bioorg Med Chem Lett 23: 6588-92 (2013)


Article DOI: 10.1016/j.bmcl.2013.10.057
BindingDB Entry DOI: 10.7270/Q2QZ2CFX
More data for this
Ligand-Target Pair