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BDBM50444413 CHEMBL3091583

SMILES: OC(=O)c1ccc(NC(=O)[C@H](CC2CCCCC2)n2cnc(c2)S(=O)(=O)C2CCC2)nc1

InChI Key: InChIKey=HFXDKQDCOWWEDC-SFHVURJKSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50444413   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glucokinase/Glucokinase regulatory protein


(Homo sapiens (Human))
BDBM50444413
PNG
(CHEMBL3091583)
Show SMILES OC(=O)c1ccc(NC(=O)[C@H](CC2CCCCC2)n2cnc(c2)S(=O)(=O)C2CCC2)nc1 |r|
Show InChI InChI=1S/C22H28N4O5S/c27-21(25-19-10-9-16(12-23-19)22(28)29)18(11-15-5-2-1-3-6-15)26-13-20(24-14-26)32(30,31)17-7-4-8-17/h9-10,12-15,17-18H,1-8,11H2,(H,28,29)(H,23,25,27)/t18-/m0/s1
PDB
MMDB

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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 227n/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Activation of recombinant human glucokinase by G6PDH/NADP coupled assay


Bioorg Med Chem Lett 23: 6588-92 (2013)


Article DOI: 10.1016/j.bmcl.2013.10.057
BindingDB Entry DOI: 10.7270/Q2QZ2CFX
More data for this
Ligand-Target Pair