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SMILES: C1C[C@H](c2ccccc2-c2ccccc2)n2cncc2C1

InChI Key: InChIKey=OBOHLLUZZMDIOB-LJQANCHMSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50444570   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cytochrome P450 11B2, mitochondrial


(Homo sapiens (Human))		BDBM50444570
PNG
(CHEMBL3099699)
Show SMILES C1C[C@H](c2ccccc2-c2ccccc2)n2cncc2C1 |r|
Show InChI InChI=1S/C19H18N2/c1-2-7-15(8-3-1)17-10-4-5-11-18(17)19-12-6-9-16-13-20-14-21(16)19/h1-5,7-8,10-11,13-14,19H,6,9,12H2/t19-/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
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CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 37n/an/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Inhibition of CYP11B2 in human NCI-H295R cells assessed as inhibition of angiotensin-2-induced aldosterone production after 24 hrs by RIA

ACS Med Chem Lett 4: 1203-7 (2013)


Article DOI: 10.1021/ml400324c
BindingDB Entry DOI: 10.7270/Q2NZ8938
More data for this
Ligand-Target Pair