BDBM50444898 CHEMBL3099625

SMILES: [#6](-[#6]-[#7]-1-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-1)-[#8]-c1ccc(cc1)-[#6](=[#6]-1/[#6]-[#6]-[#6]-[#6]-[#6]-1)\c1ccc(-[#8]-[#6]-[#6]-[#7]-2-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-2)cc1

InChI Key: InChIKey=SVUWLVVPTWMTJH-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50444898   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
20S proteasome chymotrypsin-like (Homo sapiens (Human))	BDBM50444898 (CHEMBL3099625) Show SMILES [#6](-[#6]-[#7]-1-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-1)-[#8]-c1ccc(cc1)-[#6](=[#6]-1/[#6]-[#6]-[#6]-[#6]-[#6]-1)\c1ccc(-[#8]-[#6]-[#6]-[#7]-2-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-2)cc1 Show InChI InChI=1S/C35H50N2O2/c1-2-9-23-36(22-8-1)26-28-38-33-18-14-31(15-19-33)35(30-12-6-5-7-13-30)32-16-20-34(21-17-32)39-29-27-37-24-10-3-4-11-25-37/h14-21H,1-13,22-29H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.19E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Bio-Science and Technology Curated by ChEMBL					Assay Description Inhibition of chymotrypsin-like activity of human 20S proteasome beta 5 subunit assessed as hydrolysis of succinyl-LLVY-AMC fluorogenic substrate mea...				Eur J Med Chem 71: 290-305 (2014) Article DOI: 10.1016/j.ejmech.2013.11.009 BindingDB Entry DOI: 10.7270/Q2222W81
					More data for this Ligand-Target Pair
Proteasome component C5 (Homo sapiens (Human))	BDBM50444898 (CHEMBL3099625) Show SMILES [#6](-[#6]-[#7]-1-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-1)-[#8]-c1ccc(cc1)-[#6](=[#6]-1/[#6]-[#6]-[#6]-[#6]-[#6]-1)\c1ccc(-[#8]-[#6]-[#6]-[#7]-2-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-2)cc1 Show InChI InChI=1S/C35H50N2O2/c1-2-9-23-36(22-8-1)26-28-38-33-18-14-31(15-19-33)35(30-12-6-5-7-13-30)32-16-20-34(21-17-32)39-29-27-37-24-10-3-4-11-25-37/h14-21H,1-13,22-29H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	890	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Bio-Science and Technology Curated by ChEMBL					Assay Description Inhibition of PGPH-like activity of human 20S proteasome beta 1 subunit assessed as hydrolysis of Z-LLE-AMC fluorogenic substrate measured for 1 hr b...				Eur J Med Chem 71: 290-305 (2014) Article DOI: 10.1016/j.ejmech.2013.11.009 BindingDB Entry DOI: 10.7270/Q2222W81
					More data for this Ligand-Target Pair
Proteasome Macropain subunit (Homo sapiens (Human))	BDBM50444898 (CHEMBL3099625) Show SMILES [#6](-[#6]-[#7]-1-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-1)-[#8]-c1ccc(cc1)-[#6](=[#6]-1/[#6]-[#6]-[#6]-[#6]-[#6]-1)\c1ccc(-[#8]-[#6]-[#6]-[#7]-2-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-2)cc1 Show InChI InChI=1S/C35H50N2O2/c1-2-9-23-36(22-8-1)26-28-38-33-18-14-31(15-19-33)35(30-12-6-5-7-13-30)32-16-20-34(21-17-32)39-29-27-37-24-10-3-4-11-25-37/h14-21H,1-13,22-29H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.18E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Bio-Science and Technology Curated by ChEMBL					Assay Description Inhibition of trypsin-like activity of human 20S proteasome beta 2 subunit assessed as hydrolysis of Boc-LRR-AMC fluorogenic substrate measured for 1...				Eur J Med Chem 71: 290-305 (2014) Article DOI: 10.1016/j.ejmech.2013.11.009 BindingDB Entry DOI: 10.7270/Q2222W81
					More data for this Ligand-Target Pair