BDBM50445130 CHEMBL3103859

SMILES: N[C@H]1CCCN(C1)c1ccncc1NC(=O)c1nc(Oc2ccccc2)ccc1N

InChI Key: InChIKey=ITEIREYZTCHMHP-HNNXBMFYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50445130   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50445130 (CHEMBL3103859) Show SMILES N[C@H]1CCCN(C1)c1ccncc1NC(=O)c1nc(Oc2ccccc2)ccc1N |r| Show InChI InChI=1S/C22H24N6O2/c23-15-5-4-12-28(14-15)19-10-11-25-13-18(19)26-22(29)21-17(24)8-9-20(27-21)30-16-6-2-1-3-7-16/h1-3,6-11,13,15H,4-5,12,14,23-24H2,(H,26,29)/t15-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of PIM1 (unknown origin)				ACS Med Chem Lett 4: 1193-7 (2013) Article DOI: 10.1021/ml400307j BindingDB Entry DOI: 10.7270/Q23X8840
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM50445130 (CHEMBL3103859) Show SMILES N[C@H]1CCCN(C1)c1ccncc1NC(=O)c1nc(Oc2ccccc2)ccc1N |r| Show InChI InChI=1S/C22H24N6O2/c23-15-5-4-12-28(14-15)19-10-11-25-13-18(19)26-22(29)21-17(24)8-9-20(27-21)30-16-6-2-1-3-7-16/h1-3,6-11,13,15H,4-5,12,14,23-24H2,(H,26,29)/t15-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of PIM3 (unknown origin)				ACS Med Chem Lett 4: 1193-7 (2013) Article DOI: 10.1021/ml400307j BindingDB Entry DOI: 10.7270/Q23X8840
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50445130 (CHEMBL3103859) Show SMILES N[C@H]1CCCN(C1)c1ccncc1NC(=O)c1nc(Oc2ccccc2)ccc1N |r| Show InChI InChI=1S/C22H24N6O2/c23-15-5-4-12-28(14-15)19-10-11-25-13-18(19)26-22(29)21-17(24)8-9-20(27-21)30-16-6-2-1-3-7-16/h1-3,6-11,13,15H,4-5,12,14,23-24H2,(H,26,29)/t15-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	122	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of PIM2 (unknown origin)				ACS Med Chem Lett 4: 1193-7 (2013) Article DOI: 10.1021/ml400307j BindingDB Entry DOI: 10.7270/Q23X8840
					More data for this Ligand-Target Pair