BDBM50445134 CHEMBL3103858

SMILES: N[C@H]1CCCN(C1)c1ccncc1NC(=O)c1ncccc1N

InChI Key: InChIKey=CXGNKWVDMVOVTL-NSHDSACASA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50445134   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50445134 (CHEMBL3103858) Show SMILES N[C@H]1CCCN(C1)c1ccncc1NC(=O)c1ncccc1N |r| Show InChI InChI=1S/C16H20N6O/c17-11-3-2-8-22(10-11)14-5-7-19-9-13(14)21-16(23)15-12(18)4-1-6-20-15/h1,4-7,9,11H,2-3,8,10,17-18H2,(H,21,23)/t11-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of PIM1 (unknown origin)				ACS Med Chem Lett 4: 1193-7 (2013) Article DOI: 10.1021/ml400307j BindingDB Entry DOI: 10.7270/Q23X8840
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM50445134 (CHEMBL3103858) Show SMILES N[C@H]1CCCN(C1)c1ccncc1NC(=O)c1ncccc1N |r| Show InChI InChI=1S/C16H20N6O/c17-11-3-2-8-22(10-11)14-5-7-19-9-13(14)21-16(23)15-12(18)4-1-6-20-15/h1,4-7,9,11H,2-3,8,10,17-18H2,(H,21,23)/t11-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of PIM3 (unknown origin)				ACS Med Chem Lett 4: 1193-7 (2013) Article DOI: 10.1021/ml400307j BindingDB Entry DOI: 10.7270/Q23X8840
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50445134 (CHEMBL3103858) Show SMILES N[C@H]1CCCN(C1)c1ccncc1NC(=O)c1ncccc1N |r| Show InChI InChI=1S/C16H20N6O/c17-11-3-2-8-22(10-11)14-5-7-19-9-13(14)21-16(23)15-12(18)4-1-6-20-15/h1,4-7,9,11H,2-3,8,10,17-18H2,(H,21,23)/t11-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of PIM2 (unknown origin)				ACS Med Chem Lett 4: 1193-7 (2013) Article DOI: 10.1021/ml400307j BindingDB Entry DOI: 10.7270/Q23X8840
					More data for this Ligand-Target Pair