BDBM50445993 CHEMBL3103127

SMILES: Oc1cc2[nH]cc(C(=O)CN3CCC(Cc4ccc(F)cc4)CC3)c2cc1O

InChI Key: InChIKey=LQKMMHFPUJBOLC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50445993   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM50445993 (CHEMBL3103127) Show SMILES Oc1cc2[nH]cc(C(=O)CN3CCC(Cc4ccc(F)cc4)CC3)c2cc1O Show InChI InChI=1S/C22H23FN2O3/c23-16-3-1-14(2-4-16)9-15-5-7-25(8-6-15)13-22(28)18-12-24-19-11-21(27)20(26)10-17(18)19/h1-4,10-12,15,24,26-27H,5-9,13H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Messina Curated by ChEMBL					Assay Description Displacement of [3H]Ifenprodil from NMDA receptor GluN2B subunit in Wistar rat cerebral cortex				Bioorg Med Chem 22: 1040-8 (2014) Article DOI: 10.1016/j.bmc.2013.12.040 BindingDB Entry DOI: 10.7270/Q29888GS
					More data for this Ligand-Target Pair