BDBM50446113 CHEMBL3108846

SMILES: Cc1cc(NS(=O)(=O)c2ccc(NC(=O)Cc3ccc(Cl)c(c3)C(F)(F)F)cc2)no1

InChI Key: InChIKey=PNGFEWXVIVQHLC-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50446113   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
6-phospho-1-fructokinase (Trypanosoma brucei)	BDBM50446113 (CHEMBL3108846) Show SMILES Cc1cc(NS(=O)(=O)c2ccc(NC(=O)Cc3ccc(Cl)c(c3)C(F)(F)F)cc2)no1 Show InChI InChI=1S/C19H15ClF3N3O4S/c1-11-8-17(25-30-11)26-31(28,29)14-5-3-13(4-6-14)24-18(27)10-12-2-7-16(20)15(9-12)19(21,22)23/h2-9H,10H2,1H3,(H,24,27)(H,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	680	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei PFK-mediated ADP production using ATP/fructose-6-phosphate as substrate by luciferase based luminescence assay				ACS Med Chem Lett 5: 12-7 (2014) BindingDB Entry DOI: 10.7270/Q2X34ZX7
					More data for this Ligand-Target Pair
6-phospho-1-fructokinase, putative (Trypanosoma cruzi)	BDBM50446113 (CHEMBL3108846) Show SMILES Cc1cc(NS(=O)(=O)c2ccc(NC(=O)Cc3ccc(Cl)c(c3)C(F)(F)F)cc2)no1 Show InChI InChI=1S/C19H15ClF3N3O4S/c1-11-8-17(25-30-11)26-31(28,29)14-5-3-13(4-6-14)24-18(27)10-12-2-7-16(20)15(9-12)19(21,22)23/h2-9H,10H2,1H3,(H,24,27)(H,25,26)	GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	920	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi PFK				ACS Med Chem Lett 5: 12-7 (2014) BindingDB Entry DOI: 10.7270/Q2X34ZX7
					More data for this Ligand-Target Pair