BDBM50446115 CHEMBL3108844

SMILES: Cc1cc(NS(=O)(=O)c2ccc(NC(=O)Cc3ccc(Cl)cc3)cc2)no1

InChI Key: InChIKey=HMDNFPXVKUMLSW-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50446115   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
6-phospho-1-fructokinase (Trypanosoma brucei)	BDBM50446115 (CHEMBL3108844) Show SMILES Cc1cc(NS(=O)(=O)c2ccc(NC(=O)Cc3ccc(Cl)cc3)cc2)no1 Show InChI InChI=1S/C18H16ClN3O4S/c1-12-10-17(21-26-12)22-27(24,25)16-8-6-15(7-9-16)20-18(23)11-13-2-4-14(19)5-3-13/h2-10H,11H2,1H3,(H,20,23)(H,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.83E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei PFK-mediated ADP production using ATP/fructose-6-phosphate as substrate by luciferase based luminescence assay				ACS Med Chem Lett 5: 12-7 (2014) BindingDB Entry DOI: 10.7270/Q2X34ZX7
					More data for this Ligand-Target Pair
6-phospho-1-fructokinase, putative (Trypanosoma cruzi)	BDBM50446115 (CHEMBL3108844) Show SMILES Cc1cc(NS(=O)(=O)c2ccc(NC(=O)Cc3ccc(Cl)cc3)cc2)no1 Show InChI InChI=1S/C18H16ClN3O4S/c1-12-10-17(21-26-12)22-27(24,25)16-8-6-15(7-9-16)20-18(23)11-13-2-4-14(19)5-3-13/h2-10H,11H2,1H3,(H,20,23)(H,21,22)	GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.46E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi PFK				ACS Med Chem Lett 5: 12-7 (2014) BindingDB Entry DOI: 10.7270/Q2X34ZX7
					More data for this Ligand-Target Pair