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BDBM50446116 CHEMBL3108843

SMILES: Cc1cc(NS(=O)(=O)c2ccc(NC(=O)Cc3cccc(Cl)c3)cc2)no1

InChI Key: InChIKey=GZRSQXWGTRMGFV-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50446116   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
6-phospho-1-fructokinase


(Trypanosoma brucei)
BDBM50446116
PNG
(CHEMBL3108843)
Show SMILES Cc1cc(NS(=O)(=O)c2ccc(NC(=O)Cc3cccc(Cl)c3)cc2)no1
Show InChI InChI=1S/C18H16ClN3O4S/c1-12-9-17(21-26-12)22-27(24,25)16-7-5-15(6-8-16)20-18(23)11-13-3-2-4-14(19)10-13/h2-10H,11H2,1H3,(H,20,23)(H,21,22)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

n/an/a 7.30E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of Trypanosoma brucei PFK-mediated ADP production using ATP/fructose-6-phosphate as substrate by luciferase based luminescence assay


Citation and Details
More data for this
Ligand-Target Pair
6-phospho-1-fructokinase, putative


(Trypanosoma cruzi)
BDBM50446116
PNG
(CHEMBL3108843)
Show SMILES Cc1cc(NS(=O)(=O)c2ccc(NC(=O)Cc3cccc(Cl)c3)cc2)no1
Show InChI InChI=1S/C18H16ClN3O4S/c1-12-9-17(21-26-12)22-27(24,25)16-7-5-15(6-8-16)20-18(23)11-13-3-2-4-14(19)10-13/h2-10H,11H2,1H3,(H,20,23)(H,21,22)
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

n/an/a 2.59E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of Trypanosoma cruzi PFK


Citation and Details
More data for this
Ligand-Target Pair