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BDBM50446125 CHEMBL3108834

SMILES: Cc1cc(NC(=O)c2csc(NC(=O)Cc3ccc(Cl)c(Cl)c3)n2)no1

InChI Key: InChIKey=UPNLZZGYTQBGLI-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50446125   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
6-phospho-1-fructokinase


(Trypanosoma brucei)
BDBM50446125
PNG
(CHEMBL3108834)
Show SMILES Cc1cc(NC(=O)c2csc(NC(=O)Cc3ccc(Cl)c(Cl)c3)n2)no1
Show InChI InChI=1S/C16H12Cl2N4O3S/c1-8-4-13(22-25-8)20-15(24)12-7-26-16(19-12)21-14(23)6-9-2-3-10(17)11(18)5-9/h2-5,7H,6H2,1H3,(H,19,21,23)(H,20,22,24)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
n/an/a>5.70E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of Trypanosoma brucei PFK-mediated ADP production using ATP/fructose-6-phosphate as substrate by luciferase based luminescence assay


Citation and Details
More data for this
Ligand-Target Pair
6-phospho-1-fructokinase, putative


(Trypanosoma cruzi)
BDBM50446125
PNG
(CHEMBL3108834)
Show SMILES Cc1cc(NC(=O)c2csc(NC(=O)Cc3ccc(Cl)c(Cl)c3)n2)no1
Show InChI InChI=1S/C16H12Cl2N4O3S/c1-8-4-13(22-25-8)20-15(24)12-7-26-16(19-12)21-14(23)6-9-2-3-10(17)11(18)5-9/h2-5,7H,6H2,1H3,(H,19,21,23)(H,20,22,24)
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
n/an/a>5.70E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of Trypanosoma cruzi PFK


Citation and Details
More data for this
Ligand-Target Pair