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BDBM50446541 CHEMBL3110185

SMILES: CN(C)c1ccc(CN2C(=O)c3cccc4cc(cc(C2=O)c34)S([O-])(=O)=O)cc1

InChI Key: InChIKey=WFFYLLXTHWBJNA-UHFFFAOYSA-M

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50446541   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Clathrin heavy chain 1


(Homo sapiens (Human))
BDBM50446541
PNG
(CHEMBL3110185)
Show SMILES CN(C)c1ccc(CN2C(=O)c3cccc4cc(cc(C2=O)c34)S([O-])(=O)=O)cc1
Show InChI InChI=1S/C21H18N2O5S/c1-22(2)15-8-6-13(7-9-15)12-23-20(24)17-5-3-4-14-10-16(29(26,27)28)11-18(19(14)17)21(23)25/h3-11H,12H2,1-2H3,(H,26,27,28)/p-1
PDB
MMDB

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KEGG

UniProtKB/SwissProt

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antibodypedia
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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.00E+5n/an/an/an/an/an/a



The University of Newcastle

Curated by ChEMBL


Assay Description
Inhibition of recombinant GST-tagged clathrin heavy chain (unknown origin) after 1 hr by ELISA


J Med Chem 57: 131-43 (2014)


Article DOI: 10.1021/jm4015263
More data for this
Ligand-Target Pair