BDBM50446549 CHEMBL3110180

SMILES: Nc1ccccc1CN1C(=O)c2cccc3cc(cc(C1=O)c23)S([O-])(=O)=O

InChI Key: InChIKey=IJJBWZQVXRAXBC-UHFFFAOYSA-M

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50446549   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Clathrin heavy chain 1 (Homo sapiens (Human))	BDBM50446549 (CHEMBL3110180) Show SMILES Nc1ccccc1CN1C(=O)c2cccc3cc(cc(C1=O)c23)S([O-])(=O)=O Show InChI InChI=1S/C19H14N2O5S/c20-16-7-2-1-4-12(16)10-21-18(22)14-6-3-5-11-8-13(27(24,25)26)9-15(17(11)14)19(21)23/h1-9H,10,20H2,(H,24,25,26)/p-1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibition of recombinant GST-tagged clathrin heavy chain (unknown origin) after 1 hr by ELISA				J Med Chem 57: 131-43 (2014) Article DOI: 10.1021/jm4015263 BindingDB Entry DOI: 10.7270/Q2HQ41DT
					More data for this Ligand-Target Pair