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SMILES: CC(C)(C)NC(c1ccc(Cl)cc1)c1ccc(cc1)-c1cn[nH]c1

InChI Key: InChIKey=PCJDDIHNGFLMPX-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50447157   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50447157 (CHEMBL3112595) Show SMILES CC(C)(C)NC(c1ccc(Cl)cc1)c1ccc(cc1)-c1cn[nH]c1 Show InChI InChI=1S/C20H22ClN3/c1-20(2,3)24-19(16-8-10-18(21)11-9-16)15-6-4-14(5-7-15)17-12-22-23-13-17/h4-13,19,24H,1-3H3,(H,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang University Curated by ChEMBL					Assay Description Inhibition of Akt1 (unknown origin) using ATP/eNOS as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by fluo...				Eur J Med Chem 73: 167-76 (2014) Article DOI: 10.1016/j.ejmech.2013.11.036 BindingDB Entry DOI: 10.7270/Q2BR8TNS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM50447157 (CHEMBL3112595) Show SMILES CC(C)(C)NC(c1ccc(Cl)cc1)c1ccc(cc1)-c1cn[nH]c1 Show InChI InChI=1S/C20H22ClN3/c1-20(2,3)24-19(16-8-10-18(21)11-9-16)15-6-4-14(5-7-15)17-12-22-23-13-17/h4-13,19,24H,1-3H3,(H,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	880	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang University Curated by ChEMBL					Assay Description Inhibition of BRAF1 (unknown origin)				Eur J Med Chem 73: 167-76 (2014) Article DOI: 10.1016/j.ejmech.2013.11.036 BindingDB Entry DOI: 10.7270/Q2BR8TNS
					More data for this Ligand-Target Pair