BDBM50447158 CHEMBL3113150

SMILES: NCCNC(c1ccc(Cl)cc1)c1ccc(cc1)-c1cn[nH]c1

InChI Key: InChIKey=WYQNADNUGPFGRG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50447158   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50447158 (CHEMBL3113150) Show SMILES NCCNC(c1ccc(Cl)cc1)c1ccc(cc1)-c1cn[nH]c1 Show InChI InChI=1S/C18H19ClN4/c19-17-7-5-15(6-8-17)18(21-10-9-20)14-3-1-13(2-4-14)16-11-22-23-12-16/h1-8,11-12,18,21H,9-10,20H2,(H,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	820	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang University Curated by ChEMBL					Assay Description Inhibition of Akt1 (unknown origin) using ATP/eNOS as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by fluo...				Eur J Med Chem 73: 167-76 (2014) Article DOI: 10.1016/j.ejmech.2013.11.036 BindingDB Entry DOI: 10.7270/Q2BR8TNS
					More data for this Ligand-Target Pair