BDBM50447162 CHEMBL3113145

SMILES: Clc1ccc(cc1)C(NC1CC1)c1ccc(cc1)-c1cn[nH]c1

InChI Key: InChIKey=MXKMQPQCKJWTCJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50447162   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50447162 (CHEMBL3113145) Show SMILES Clc1ccc(cc1)C(NC1CC1)c1ccc(cc1)-c1cn[nH]c1 Show InChI InChI=1S/C19H18ClN3/c20-17-7-5-15(6-8-17)19(23-18-9-10-18)14-3-1-13(2-4-14)16-11-21-22-12-16/h1-8,11-12,18-19,23H,9-10H2,(H,21,22)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang University Curated by ChEMBL					Assay Description Inhibition of Akt1 (unknown origin) using ATP/eNOS as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by fluo...				Eur J Med Chem 73: 167-76 (2014) Article DOI: 10.1016/j.ejmech.2013.11.036 BindingDB Entry DOI: 10.7270/Q2BR8TNS
					More data for this Ligand-Target Pair