BDBM50447167 CHEMBL3113140

SMILES: CC(C)CNC(c1ccc(Cl)cc1)c1ccc(cc1)-c1ncnc2nc[nH]c12

InChI Key: InChIKey=ASKYTOPBQXFCBV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50447167   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50447167 (CHEMBL3113140) Show SMILES CC(C)CNC(c1ccc(Cl)cc1)c1ccc(cc1)-c1ncnc2nc[nH]c12 Show InChI InChI=1S/C22H22ClN5/c1-14(2)11-24-19(16-7-9-18(23)10-8-16)15-3-5-17(6-4-15)20-21-22(27-12-25-20)28-13-26-21/h3-10,12-14,19,24H,11H2,1-2H3,(H,25,26,27,28)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	740	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang University Curated by ChEMBL					Assay Description Inhibition of Akt1 (unknown origin) using ATP/eNOS as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by fluo...				Eur J Med Chem 73: 167-76 (2014) Article DOI: 10.1016/j.ejmech.2013.11.036 BindingDB Entry DOI: 10.7270/Q2BR8TNS
					More data for this Ligand-Target Pair