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SMILES: CC(C)(C)NC(c1ccc(Cl)cc1)c1ccc(cc1)-c1ccncc1

InChI Key: InChIKey=DYNMXXYTOFUDLF-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50447170   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
RAC-alpha serine/threonine-protein kinase


(Homo sapiens (Human))		BDBM50447170
PNG
(CHEMBL3113136)
Show SMILES CC(C)(C)NC(c1ccc(Cl)cc1)c1ccc(cc1)-c1ccncc1
Show InChI InChI=1S/C22H23ClN2/c1-22(2,3)25-21(19-8-10-20(23)11-9-19)18-6-4-16(5-7-18)17-12-14-24-15-13-17/h4-15,21,25H,1-3H3
PDB

UniProtKB/SwissProt

antibodypedia
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AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 170n/an/an/an/an/an/a



Zhejiang University

Curated by ChEMBL


Assay Description
Inhibition of Akt1 (unknown origin) using ATP/eNOS as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by fluo...

Eur J Med Chem 73: 167-76 (2014)


Article DOI: 10.1016/j.ejmech.2013.11.036
BindingDB Entry DOI: 10.7270/Q2BR8TNS
More data for this
Ligand-Target Pair