BDBM50447261 CHEMBL1945694

SMILES: Cc1cc2ncn(Cc3ccc(Cl)cc3)c2cc1C

InChI Key: InChIKey=AGMQHEBJQCVRFK-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50447261   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Enoyl-acyl carrier reductase (Toxoplasma gondii)	BDBM50447261 (CHEMBL1945694) Show SMILES Cc1cc2ncn(Cc3ccc(Cl)cc3)c2cc1C Show InChI InChI=1S/C16H15ClN2/c1-11-7-15-16(8-12(11)2)19(10-18-15)9-13-3-5-14(17)6-4-13/h3-8,10H,9H2,1-2H3	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Leeds Curated by ChEMBL					Assay Description Inhibition of Toxoplasma gondii enoyl-ACP reductase-NADH complex				Bioorg Med Chem Lett 24: 911-6 (2014) Article DOI: 10.1016/j.bmcl.2013.12.066 BindingDB Entry DOI: 10.7270/Q2TT4SF6
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50447261 (CHEMBL1945694) Show SMILES Cc1cc2ncn(Cc3ccc(Cl)cc3)c2cc1C Show InChI InChI=1S/C16H15ClN2/c1-11-7-15-16(8-12(11)2)19(10-18-15)9-13-3-5-14(17)6-4-13/h3-8,10H,9H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Board of Trustees of the Leland Stanford Junion University US Patent					Assay Description Drugs belonging to different classes have been shown to be associated with QT prolongation and in some cases serious ventricular arrhythmias. The mos...				US Patent US8975247 (2015) BindingDB Entry DOI: 10.7270/Q26M35J2
					More data for this Ligand-Target Pair