BDBM50447413 CHEMBL3115157
SMILES: Cc1ccc(C)c(NC(=O)CNS(=O)(=O)c2ccc3[nH]c(=O)oc3c2)c1
InChI Key: InChIKey=NOEHWVSISATFED-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Intestinal alkaline phosphatase (Mus musculus) | BDBM50447413 (CHEMBL3115157) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Sanford-Burnham Medical Research Institute Curated by ChEMBL | Assay Description Competitive inhibition of mouse duodenal-specific FLAG-tagged IAP expressed in African green monkey COS1 cells using p-nitrophenyl phosphate as subst... | Bioorg Med Chem Lett 24: 1000-4 (2014) Article DOI: 10.1016/j.bmcl.2013.12.043 BindingDB Entry DOI: 10.7270/Q2ST7RB8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alkaline phosphatase, placental-like (Mus musculus) | BDBM50447413 (CHEMBL3115157) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.11E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sanford-Burnham Medical Research Institute Curated by ChEMBL | Assay Description Inhibition of mouse EAP using p-nitrophenyl phosphate as substrate after 30 mins by chemiluminescence assay | Bioorg Med Chem Lett 24: 1000-4 (2014) Article DOI: 10.1016/j.bmcl.2013.12.043 BindingDB Entry DOI: 10.7270/Q2ST7RB8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Intestinal alkaline phosphatase (Mus musculus) | BDBM50447413 (CHEMBL3115157) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 540 | n/a | n/a | n/a | n/a | n/a | n/a |
Sanford-Burnham Medical Research Institute Curated by ChEMBL | Assay Description Inhibition of mouse duodenal-specific FLAG-tagged IAP expressed in African green monkey COS1 cells after 30 mins by chemiluminescence assay | Bioorg Med Chem Lett 24: 1000-4 (2014) Article DOI: 10.1016/j.bmcl.2013.12.043 BindingDB Entry DOI: 10.7270/Q2ST7RB8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alkaline phosphatase placental type (Homo sapiens (Human)) | BDBM50447413 (CHEMBL3115157) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Sanford-Burnham Medical Research Institute Curated by ChEMBL | Assay Description Inhibition of FLAG-tagged PLAP (unknown origin) expressed in African green monkey COS1 cells after 30 mins by chemiluminescence assay | Bioorg Med Chem Lett 24: 1000-4 (2014) Article DOI: 10.1016/j.bmcl.2013.12.043 BindingDB Entry DOI: 10.7270/Q2ST7RB8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alkaline phosphatase, tissue-nonspecific isozyme (Homo sapiens (Human)) | BDBM50447413 (CHEMBL3115157) | KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sanford-Burnham Medical Research Institute Curated by ChEMBL | Assay Description Inhibition of FLAG-tagged TNAP (unknown origin) expressed in African green monkey COS1 cells after 30 mins by chemiluminescence assay | Bioorg Med Chem Lett 24: 1000-4 (2014) Article DOI: 10.1016/j.bmcl.2013.12.043 BindingDB Entry DOI: 10.7270/Q2ST7RB8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Intestinal alkaline phosphatase (Homo sapiens (Human)) | BDBM50447413 (CHEMBL3115157) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.76E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sanford-Burnham Medical Research Institute Curated by ChEMBL | Assay Description Inhibition of human FLAG-tagged IAP expressed in African green monkey COS1 cells using p-nitrophenyl phosphate as substrate after 30 mins by chemilum... | Bioorg Med Chem Lett 24: 1000-4 (2014) Article DOI: 10.1016/j.bmcl.2013.12.043 BindingDB Entry DOI: 10.7270/Q2ST7RB8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Intestinal alkaline phosphatase (Mus musculus) | BDBM50447413 (CHEMBL3115157) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sanford-Burnham Medical Research Institute Curated by ChEMBL | Assay Description Inhibition of mouse duodenal-specific FLAG-tagged IAP expressed in African green monkey COS1 cells using p-nitrophenyl phosphate as substrate after 3... | Bioorg Med Chem Lett 24: 1000-4 (2014) Article DOI: 10.1016/j.bmcl.2013.12.043 BindingDB Entry DOI: 10.7270/Q2ST7RB8 | |||||||||||
More data for this Ligand-Target Pair |