BDBM50447745 CHEMBL3113274
SMILES: Fc1cc(F)cc(c1)-c1ccnc(n1)N1CCN(CC1)C(=O)Nc1cccnn1
InChI Key: InChIKey=RZQZVKOTLXGHBX-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Fatty-acid amide hydrolase 1 (Homo sapiens (Human)) | BDBM50447745 (CHEMBL3113274) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.0800 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Ltd Curated by ChEMBL | Assay Description Apparent inhibition of human FAAH expressed in CHOK1 cells using AMCAA as substrate after 30 mins by fluorescence assay | Bioorg Med Chem 22: 1468-78 (2014) Article DOI: 10.1016/j.bmc.2013.12.023 BindingDB Entry DOI: 10.7270/Q20C4X77 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty-acid amide hydrolase 1 (aa 30-579) (Rattus norvegicus (rat)) | BDBM50447745 (CHEMBL3113274) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.340 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Ltd Curated by ChEMBL | Assay Description Apparent inhibition of rat FAAH using AMCAA as substrate after 30 mins by fluorescence assay | Bioorg Med Chem 22: 1468-78 (2014) Article DOI: 10.1016/j.bmc.2013.12.023 BindingDB Entry DOI: 10.7270/Q20C4X77 | |||||||||||
More data for this Ligand-Target Pair |