BDBM50447750 CHEMBL3113269

SMILES: Fc1ccc(c(F)c1)-c1cc(ncn1)N1CCN(CC1)C(=O)Nc1cccnn1

InChI Key: InChIKey=QMLUKFKNJYGUOW-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50447750   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50447750 (CHEMBL3113269) Show SMILES Fc1ccc(c(F)c1)-c1cc(ncn1)N1CCN(CC1)C(=O)Nc1cccnn1 Show InChI InChI=1S/C19H17F2N7O/c20-13-3-4-14(15(21)10-13)16-11-18(23-12-22-16)27-6-8-28(9-7-27)19(29)25-17-2-1-5-24-26-17/h1-5,10-12H,6-9H2,(H,25,26,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd Curated by ChEMBL					Assay Description Apparent inhibition of human FAAH expressed in CHOK1 cells using AMCAA as substrate after 30 mins by fluorescence assay				Bioorg Med Chem 22: 1468-78 (2014) Article DOI: 10.1016/j.bmc.2013.12.023 BindingDB Entry DOI: 10.7270/Q20C4X77
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (aa 30-579) (Rattus norvegicus (rat))	BDBM50447750 (CHEMBL3113269) Show SMILES Fc1ccc(c(F)c1)-c1cc(ncn1)N1CCN(CC1)C(=O)Nc1cccnn1 Show InChI InChI=1S/C19H17F2N7O/c20-13-3-4-14(15(21)10-13)16-11-18(23-12-22-16)27-6-8-28(9-7-27)19(29)25-17-2-1-5-24-26-17/h1-5,10-12H,6-9H2,(H,25,26,29)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd Curated by ChEMBL					Assay Description Apparent inhibition of rat FAAH using AMCAA as substrate after 30 mins by fluorescence assay				Bioorg Med Chem 22: 1468-78 (2014) Article DOI: 10.1016/j.bmc.2013.12.023 BindingDB Entry DOI: 10.7270/Q20C4X77
					More data for this Ligand-Target Pair