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SMILES: CNc1nc(Nc2cn(nc2C)C(C)(C)C(=O)NCC(F)(F)F)ncc1C(F)(F)F

InChI Key: InChIKey=PDECQZVCQHUUND-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50448119   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Leucine-rich repeat serine/threonine-protein kinase 2


(Homo sapiens (Human))		BDBM50448119
PNG
(CHEMBL3122112)
Show SMILES CNc1nc(Nc2cn(nc2C)C(C)(C)C(=O)NCC(F)(F)F)ncc1C(F)(F)F
Show InChI InChI=1S/C16H19F6N7O/c1-8-10(26-13-24-5-9(16(20,21)22)11(23-4)27-13)6-29(28-8)14(2,3)12(30)25-7-15(17,18)19/h5-6H,7H2,1-4H3,(H,25,30)(H2,23,24,26,27)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 53n/an/an/an/an/an/a



Genentech

Curated by ChEMBL


Assay Description
Inhibition of LRRK2 (unknown origin) phosphorylation by cell-based assay

J Med Chem 57: 921-36 (2014)


Article DOI: 10.1021/jm401654j
BindingDB Entry DOI: 10.7270/Q2N0181N
More data for this
Ligand-Target Pair