null

SMILES: CC(C)c1cc(Cn2c(C)c(C(=O)NCC(O)=O)c3ccccc23)ccc1O

InChI Key: InChIKey=KQSGCLVFDFNDIM-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50448468   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thyroid hormone receptor alpha (Homo sapiens (Human))	BDBM50448468 (CHEMBL3126378) Show SMILES CC(C)c1cc(Cn2c(C)c(C(=O)NCC(O)=O)c3ccccc23)ccc1O Show InChI InChI=1S/C22H24N2O4/c1-13(2)17-10-15(8-9-19(17)25)12-24-14(3)21(22(28)23-11-20(26)27)16-6-4-5-7-18(16)24/h4-10,13,25H,11-12H2,1-3H3,(H,23,28)(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sanwa Kagaku Kenkyusho Co., Ltd Curated by ChEMBL					Assay Description Displacement of [125I]-Triiodothyronine from human recombinant TRalpha1 ligand binding domain after 2 to 3 hrs by beta counting				Bioorg Med Chem 22: 488-98 (2013) Article DOI: 10.1016/j.bmc.2013.11.001 BindingDB Entry DOI: 10.7270/Q2H41SXN
					More data for this Ligand-Target Pair
Thyroid hormone receptor beta (Homo sapiens (Human))	BDBM50448468 (CHEMBL3126378) Show SMILES CC(C)c1cc(Cn2c(C)c(C(=O)NCC(O)=O)c3ccccc23)ccc1O Show InChI InChI=1S/C22H24N2O4/c1-13(2)17-10-15(8-9-19(17)25)12-24-14(3)21(22(28)23-11-20(26)27)16-6-4-5-7-18(16)24/h4-10,13,25H,11-12H2,1-3H3,(H,23,28)(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sanwa Kagaku Kenkyusho Co., Ltd Curated by ChEMBL					Assay Description Displacement of [125I]-Triiodothyronine from human recombinant TRbeta1 ligand binding domain after 2 to 3 hrs by beta counting				Bioorg Med Chem 22: 488-98 (2013) Article DOI: 10.1016/j.bmc.2013.11.001 BindingDB Entry DOI: 10.7270/Q2H41SXN
					More data for this Ligand-Target Pair