BDBM50448600 CHEMBL3124966

SMILES: C[C@@]1(C[C@H](Nc2ccc(cc12)C(N)=N)c1cccc(c1)-c1ccc(NS(C)(=O)=O)cc1C(O)=O)c1ccccc1

InChI Key: InChIKey=XWBQFMMPWUSKOQ-QCENPCRXSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50448600   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor XI (Homo sapiens (Human))	BDBM50448600 (CHEMBL3124966) Show SMILES C[C@@]1(C[C@H](Nc2ccc(cc12)C(N)=N)c1cccc(c1)-c1ccc(NS(C)(=O)=O)cc1C(O)=O)c1ccccc1 |r| Show InChI InChI=1S/C31H30N4O4S/c1-31(22-9-4-3-5-10-22)18-28(34-27-14-11-21(29(32)33)16-26(27)31)20-8-6-7-19(15-20)24-13-12-23(35-40(2,38)39)17-25(24)30(36)37/h3-17,28,34-35H,18H2,1-2H3,(H3,32,33)(H,36,37)/t28-,31+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Binding affinity to human factor 11a assessed as release of p-nitroaniline after 10 to 120 mins by spectrophotometric analysis				J Med Chem 57: 955-69 (2014) Article DOI: 10.1021/jm401670x BindingDB Entry DOI: 10.7270/Q2G44RTQ
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50448600 (CHEMBL3124966) Show SMILES C[C@@]1(C[C@H](Nc2ccc(cc12)C(N)=N)c1cccc(c1)-c1ccc(NS(C)(=O)=O)cc1C(O)=O)c1ccccc1 |r| Show InChI InChI=1S/C31H30N4O4S/c1-31(22-9-4-3-5-10-22)18-28(34-27-14-11-21(29(32)33)16-26(27)31)20-8-6-7-19(15-20)24-13-12-23(35-40(2,38)39)17-25(24)30(36)37/h3-17,28,34-35H,18H2,1-2H3,(H3,32,33)(H,36,37)/t28-,31+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Binding affinity to human factor 10a assessed as release of p-nitroaniline after 10 to 120 mins by spectrophotometric analysis				J Med Chem 57: 955-69 (2014) Article DOI: 10.1021/jm401670x BindingDB Entry DOI: 10.7270/Q2G44RTQ
					More data for this Ligand-Target Pair