BDBM50448764 CHEMBL3128036

SMILES: Fc1ncc(cc1-c1cccnc1)[C@H]1C[C@H]2CC[C@H]1N2

InChI Key: InChIKey=YNZDJAQJOUFZIH-UMVBOHGHSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50448764   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor Alpha-3/Beta-4 (Rattus norvegicus (Rat))	BDBM50448764 (CHEMBL3128036) Show SMILES Fc1ncc(cc1-c1cccnc1)[C@H]1C[C@H]2CC[C@H]1N2 |r,THB:4:13:16.17:19| Show InChI InChI=1S/C16H16FN3/c17-16-14(10-2-1-5-18-8-10)6-11(9-19-16)13-7-12-3-4-15(13)20-12/h1-2,5-6,8-9,12-13,15,20H,3-4,7H2/t12-,13-,15-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Antagonist activity at rat alpha3beta4 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current by two-elect...				J Med Chem 57: 836-48 (2014) Article DOI: 10.1021/jm401602p BindingDB Entry DOI: 10.7270/Q2JW8GDR
					More data for this Ligand-Target Pair