null

SMILES: CC(C)(CC(O)(Cc1cc2ncncc2[nH]1)C(F)(F)F)c1ccccc1S(C)(=O)=O

InChI Key: InChIKey=VORSJOLOEGVROH-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50449059   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM50449059 (CHEMBL3126946) Show SMILES CC(C)(CC(O)(Cc1cc2ncncc2[nH]1)C(F)(F)F)c1ccccc1S(C)(=O)=O Show InChI InChI=1S/C20H22F3N3O3S/c1-18(2,14-6-4-5-7-17(14)30(3,28)29)11-19(27,20(21,22)23)9-13-8-15-16(26-13)10-24-12-25-15/h4-8,10,12,26-27H,9,11H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Competitive binding affinity to progesterone receptor (unknown origin) expressed in baculovirus-infected cell system after 1 hr by fluorescence polar...				J Med Chem 57: 1583-98 (2014) Article DOI: 10.1021/jm4019178 BindingDB Entry DOI: 10.7270/Q23N24W5
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50449059 (CHEMBL3126946) Show SMILES CC(C)(CC(O)(Cc1cc2ncncc2[nH]1)C(F)(F)F)c1ccccc1S(C)(=O)=O Show InChI InChI=1S/C20H22F3N3O3S/c1-18(2,14-6-4-5-7-17(14)30(3,28)29)11-19(27,20(21,22)23)9-13-8-15-16(26-13)10-24-12-25-15/h4-8,10,12,26-27H,9,11H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Competitive binding affinity to mineralocorticoid receptor (unknown origin) expressed in baculovirus-infected cell system after 1 hr by fluorescence ...				J Med Chem 57: 1583-98 (2014) Article DOI: 10.1021/jm4019178 BindingDB Entry DOI: 10.7270/Q23N24W5
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50449059 (CHEMBL3126946) Show SMILES CC(C)(CC(O)(Cc1cc2ncncc2[nH]1)C(F)(F)F)c1ccccc1S(C)(=O)=O Show InChI InChI=1S/C20H22F3N3O3S/c1-18(2,14-6-4-5-7-17(14)30(3,28)29)11-19(27,20(21,22)23)9-13-8-15-16(26-13)10-24-12-25-15/h4-8,10,12,26-27H,9,11H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Transrepression activity at glucocorticoid receptor in human fibroblasts assessed as inhibition of IL-1-induced IL-6 production after 18 to 24 hrs				J Med Chem 57: 1583-98 (2014) Article DOI: 10.1021/jm4019178 BindingDB Entry DOI: 10.7270/Q23N24W5
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50449059 (CHEMBL3126946) Show SMILES CC(C)(CC(O)(Cc1cc2ncncc2[nH]1)C(F)(F)F)c1ccccc1S(C)(=O)=O Show InChI InChI=1S/C20H22F3N3O3S/c1-18(2,14-6-4-5-7-17(14)30(3,28)29)11-19(27,20(21,22)23)9-13-8-15-16(26-13)10-24-12-25-15/h4-8,10,12,26-27H,9,11H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Competitive binding affinity to glucocorticoid receptor (unknown origin) expressed in baculovirus-infected cell system after 1 hr by fluorescence pol...				J Med Chem 57: 1583-98 (2014) Article DOI: 10.1021/jm4019178 BindingDB Entry DOI: 10.7270/Q23N24W5
					More data for this Ligand-Target Pair