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SMILES: Nc1nc(cc(=O)[nH]1)-c1cccc(OC(F)(F)F)c1

InChI Key: InChIKey=XPRMWNJSRFZDPS-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50449119   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Xanthine dehydrogenase/oxidase


(Homo sapiens (Human))		BDBM50449119
PNG
(CHEMBL3127122)
Show SMILES Nc1nc(cc(=O)[nH]1)-c1cccc(OC(F)(F)F)c1
Show InChI InChI=1S/C11H8F3N3O2/c12-11(13,14)19-7-3-1-2-6(4-7)8-5-9(18)17-10(15)16-8/h1-5H,(H3,15,16,17,18)
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Article
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n/an/a 200n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of C-terminally FLAG-tagged human xanthine oxidase (amino acid 1 to 1333) expressed in baculovirus system after 15 mins by spectrophotomet...

Bioorg Med Chem Lett 24: 1315-21 (2014)


Article DOI: 10.1016/j.bmcl.2014.01.050
BindingDB Entry DOI: 10.7270/Q2V69M3N
More data for this
Ligand-Target Pair