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BDBM50449318 CHEMBL3126051

SMILES: CC(C)N1CCN([C@H]2CC[C@H](CC2)C(=O)Nc2ccc(cn2)-c2cc(F)cc(F)c2)C1=O

InChI Key: InChIKey=GDHZCBNIARZYDK-NBEIKUQISA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50449318   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neuropeptide Y receptor type 5 ( NPY Y5)


(Homo sapiens (Human))		BDBM50449318
PNG
(CHEMBL3126051)
Show SMILES CC(C)N1CCN([C@H]2CC[C@H](CC2)C(=O)Nc2ccc(cn2)-c2cc(F)cc(F)c2)C1=O |r,wU:10.13,7.6,(31.81,-39.8,;32.04,-41.33,;33.45,-41.95,;30.8,-42.22,;30.79,-43.76,;29.33,-44.23,;28.42,-42.98,;26.88,-42.97,;26.11,-44.31,;24.57,-44.3,;23.8,-42.96,;24.58,-41.64,;26.12,-41.64,;22.27,-42.96,;21.5,-41.63,;21.49,-44.29,;19.95,-44.28,;19.18,-45.62,;17.64,-45.61,;16.88,-44.27,;17.65,-42.94,;19.19,-42.95,;15.34,-44.27,;14.57,-42.93,;13.03,-42.93,;12.27,-41.6,;12.26,-44.26,;13.02,-45.6,;12.25,-46.93,;14.56,-45.6,;29.34,-41.74,;28.86,-40.28,)|
Show InChI InChI=1S/C24H28F2N4O2/c1-15(2)29-9-10-30(24(29)32)21-6-3-16(4-7-21)23(31)28-22-8-5-17(14-27-22)18-11-19(25)13-20(26)12-18/h5,8,11-16,21H,3-4,6-7,9-10H2,1-2H3,(H,27,28,31)/t16-,21+
KEGG

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PC cid
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Similars
Article
PubMed
 41n/an/an/an/an/an/an/an/a



Lundbeck Research USA, Inc.

Curated by ChEMBL


Assay Description
Displacement of [125I]PYY from human NPY5 receptor transfected in LM(tk-) cell membranes after 120 mins by solid scintillation counting

Bioorg Med Chem Lett 24: 1458-61 (2014)


Article DOI: 10.1016/j.bmcl.2014.02.023
BindingDB Entry DOI: 10.7270/Q2S75HT1
More data for this
Ligand-Target Pair