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BDBM50449326 CHEMBL3126040

SMILES: Fc1cc(F)cc(c1)-c1cnc(NC(=O)[C@@H]2CC[C@@H](CC2)N2CCCC2=O)cn1

InChI Key: InChIKey=OFLQLZVOIWKDDT-XFHMXUHZSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50449326   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neuropeptide Y receptor type 5 ( NPY Y5)


(Homo sapiens (Human))		BDBM50449326
PNG
(CHEMBL3126040)
Show SMILES Fc1cc(F)cc(c1)-c1cnc(NC(=O)[C@@H]2CC[C@@H](CC2)N2CCCC2=O)cn1 |r,wU:15.15,18.22,(14.68,-24.91,;15.45,-23.57,;14.68,-22.24,;15.45,-20.91,;14.68,-19.58,;16.99,-20.91,;17.76,-22.24,;16.99,-23.57,;19.3,-22.24,;20.08,-23.57,;21.62,-23.57,;22.39,-22.24,;23.93,-22.24,;24.7,-23.57,;24,-24.95,;26.24,-23.5,;27.07,-24.79,;28.61,-24.71,;29.31,-23.33,;28.48,-22.04,;26.93,-22.13,;30.85,-23.26,;31.69,-21.96,;33.18,-22.36,;33.26,-23.9,;31.82,-24.46,;31.42,-25.94,;21.62,-20.91,;20.08,-20.91,)|
Show InChI InChI=1S/C21H22F2N4O2/c22-15-8-14(9-16(23)10-15)18-11-25-19(12-24-18)26-21(29)13-3-5-17(6-4-13)27-7-1-2-20(27)28/h8-13,17H,1-7H2,(H,25,26,29)/t13-,17+
KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
PubMed
 6n/an/an/an/an/an/an/an/a



Lundbeck Research USA, Inc.

Curated by ChEMBL


Assay Description
Displacement of [125I]PYY from human NPY5 receptor transfected in LM(tk-) cell membranes after 120 mins by solid scintillation counting

Bioorg Med Chem Lett 24: 1458-61 (2014)


Article DOI: 10.1016/j.bmcl.2014.02.023
BindingDB Entry DOI: 10.7270/Q2S75HT1
More data for this
Ligand-Target Pair