BindingDB PrimarySearch

BDBM50450369 SIALYL LEWIS X::Sialyl LeX::Sialyl lewis-x::sLex::sialyl LewisX

SMILES: [H][C@]1(O[C@@](C[C@H](O)[C@H]1NC(C)=O)(O[C@H]1[C@@H](O)[C@@H](CO)O[C@@H](O[C@H]([C@H](O)CO)[C@H](O[C@@H]2O[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]2O)[C@@H](NC(C)=O)C=O)[C@@H]1O)C(O)=O)[C@H](O)[C@H](O)CO

InChI Key: InChIKey=LAQPKDLYOBZWBT-NYLDSJSYSA-N

Data: 39 IC50 1 Kd

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 40 hits for monomerid = 50450369
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Leukocyte adhesion molecule-1 (Homo sapiens (Human))	BDBM50450369 (SIALYL LEWIS X \| Sialyl LeX \| Sialyl lewis-x \| sLe...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Nippon Organon K.K. Curated by ChEMBL					Assay Description In vitro inhibitory activity of compound was determined against Selectin L binding by ELISA assay				Bioorg Med Chem Lett 10: 1827-30 (2000) BindingDB Entry DOI: 10.7270/Q2ZP46M8
Nippon Organon K.K. Curated by ChEMBL					More data for this Ligand-Target Pair
P-selectin/P-selectin glycoprotein ligand 1 (Homo sapiens (Human))	BDBM50450369 (SIALYL LEWIS X \| Sialyl LeX \| Sialyl lewis-x \| sLe...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.50E+6	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Montr£al Curated by ChEMBL					Assay Description Concentration required to inhibit the interaction of Selectin P and HL-60 cells				Bioorg Med Chem Lett 11: 1109-12 (2001) BindingDB Entry DOI: 10.7270/Q28C9WSC
Universit£ de Montr£al Curated by ChEMBL					More data for this Ligand-Target Pair
P-selectin/P-selectin glycoprotein ligand 1 (Homo sapiens (Human))	BDBM50450369 (SIALYL LEWIS X \| Sialyl LeX \| Sialyl lewis-x \| sLe...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Nippon Organon K.K. Curated by ChEMBL					Assay Description In vitro inhibitory activity of compound was determined against Selectin P binding by ELISA assay				Bioorg Med Chem Lett 10: 1827-30 (2000) BindingDB Entry DOI: 10.7270/Q2ZP46M8
Nippon Organon K.K. Curated by ChEMBL					More data for this Ligand-Target Pair
Selectin E (Homo sapiens (Human))	BDBM50450369 (SIALYL LEWIS X \| Sialyl LeX \| Sialyl lewis-x \| sLe...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	Article	n/a	n/a	n/a	1.00E+6	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Affinity of compound to Selectin E was determined				Bioorg Med Chem Lett 5: 2637-2642 (1995) Article DOI: 10.1016/0960-894X(95)00469-A BindingDB Entry DOI: 10.7270/Q25D8SBB
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Selectin (Homo sapiens (Human))	BDBM50450369 (SIALYL LEWIS X \| Sialyl LeX \| Sialyl lewis-x \| sLe...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.09E+6	n/a	n/a	n/a	n/a	n/a	n/a
Scripps Research Institute Curated by ChEMBL					Assay Description Compound was tested in a cell-free SLe-polyacrylamide glycoconjugate binding assay (assay B) in Selectin E				Bioorg Med Chem Lett 8: 2333-8 (1999) BindingDB Entry DOI: 10.7270/Q2NV9JR1
Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
P-selectin/P-selectin glycoprotein ligand 1 (Homo sapiens (Human))	BDBM50450369 (SIALYL LEWIS X \| Sialyl LeX \| Sialyl lewis-x \| sLe...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>3.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Scripps Research Institute Curated by ChEMBL					Assay Description Tested in a cell-free SLe-polyacrylamide glycoconjugate binding assay (assay A) in P-selectin				Bioorg Med Chem Lett 8: 2333-8 (1999) BindingDB Entry DOI: 10.7270/Q2NV9JR1
Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Selectin E (Homo sapiens (Human))	BDBM50450369 (SIALYL LEWIS X \| Sialyl LeX \| Sialyl lewis-x \| sLe...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.80E+5	n/a	n/a	n/a	n/a	n/a	n/a
Scripps Research Institute Curated by ChEMBL					Assay Description Compound was tested in a cell-free SLe-polyacrylamide glycoconjugate binding assay (assay B) in Selectin E				Bioorg Med Chem Lett 8: 2333-8 (1999) BindingDB Entry DOI: 10.7270/Q2NV9JR1
Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
P-selectin/P-selectin glycoprotein ligand 1 (Homo sapiens (Human))	BDBM50450369 (SIALYL LEWIS X \| Sialyl LeX \| Sialyl lewis-x \| sLe...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.30E+6	n/a	n/a	n/a	n/a	n/a	n/a
Scripps Research Institute Curated by ChEMBL					Assay Description Compound was tested in a cell-free SLe-polyacrylamide glycoconjugate binding assay (assay B) in P-selectin; value ranges from 1.3-2				Bioorg Med Chem Lett 8: 2333-8 (1999) BindingDB Entry DOI: 10.7270/Q2NV9JR1
Scripps Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Selectin E (Homo sapiens (Human))	BDBM50450369 (SIALYL LEWIS X \| Sialyl LeX \| Sialyl lewis-x \| sLe...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Montr£al Curated by ChEMBL					Assay Description Compound was evaluated for the Selectin E binding activity.				Bioorg Med Chem Lett 8: 2803-8 (1999) BindingDB Entry DOI: 10.7270/Q2RN38CC
Universit£ de Montr£al Curated by ChEMBL					More data for this Ligand-Target Pair
Selectin E (Homo sapiens (Human))	BDBM50450369 (SIALYL LEWIS X \| Sialyl LeX \| Sialyl lewis-x \| sLe...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	Article	n/a	n/a	5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit sialyl Lewis X binding to Selectin E was determined				Bioorg Med Chem Lett 6: 2755-2760 (1996) Article DOI: 10.1016/S0960-894X(96)00509-4 BindingDB Entry DOI: 10.7270/Q2CV4J8C
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Selectin E (Homo sapiens (Human))	BDBM50450369 (SIALYL LEWIS X \| Sialyl LeX \| Sialyl lewis-x \| sLe...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	Article	n/a	n/a	3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested for its ability to inhibit the binding to recombinant human Selectin E immobilized on SPA beads of radiolabeled HL60 cell membran...				Bioorg Med Chem Lett 6: 239-244 (1996) Article DOI: 10.1016/0960-894X(96)00008-X BindingDB Entry DOI: 10.7270/Q2VT1SMM
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Selectin E (Mus musculus)	BDBM50450369 (SIALYL LEWIS X \| Sialyl LeX \| Sialyl lewis-x \| sLe...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	Article	n/a	n/a	3.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested for its ability to inhibit sialyl Lewis X dependent binding of HL-60 cells to Selectin E fusion protein				Bioorg Med Chem Lett 6: 569-572 (1996) Article DOI: 10.1016/0960-894X(96)00071-6 BindingDB Entry DOI: 10.7270/Q2Q81D24
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Selectin E (Homo sapiens (Human))	BDBM50450369 (SIALYL LEWIS X \| Sialyl LeX \| Sialyl lewis-x \| sLe...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description In vitro inhibitory activity against binding of Selectin E to human recombinant AGP (alpha-1 acid glycoprotein) containing sLex derivative				Bioorg Med Chem Lett 11: 151-5 (2001) BindingDB Entry DOI: 10.7270/Q2G73F71
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair
Selectin E (Homo sapiens (Human))	BDBM50450369 (SIALYL LEWIS X \| Sialyl LeX \| Sialyl lewis-x \| sLe...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Montr£al Curated by ChEMBL					Assay Description Concentration required to inhibit the interaction of Selectin E and HL-60 cells				Bioorg Med Chem Lett 11: 1109-12 (2001) BindingDB Entry DOI: 10.7270/Q28C9WSC
Universit£ de Montr£al Curated by ChEMBL					More data for this Ligand-Target Pair
P-selectin/P-selectin glycoprotein ligand 1 (Homo sapiens (Human))	BDBM50450369 (SIALYL LEWIS X \| Sialyl LeX \| Sialyl lewis-x \| sLe...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Montr£al Curated by ChEMBL					Assay Description Concentration required to inhibit the interaction of Selectin P and HL-60 cells				Bioorg Med Chem Lett 11: 1109-12 (2001) BindingDB Entry DOI: 10.7270/Q28C9WSC
Universit£ de Montr£al Curated by ChEMBL					More data for this Ligand-Target Pair
Selectin E (Homo sapiens (Human))	BDBM50450369 (SIALYL LEWIS X \| Sialyl LeX \| Sialyl lewis-x \| sLe...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Monash University (Parkville Campus) Curated by ChEMBL					Assay Description Inhibitory concentration against E-selectin				Bioorg Med Chem Lett 11: 1587-90 (2001) BindingDB Entry DOI: 10.7270/Q2BP03BB
Monash University (Parkville Campus) Curated by ChEMBL					More data for this Ligand-Target Pair
Selectin E (Homo sapiens (Human))	BDBM50450369 (SIALYL LEWIS X \| Sialyl LeX \| Sialyl lewis-x \| sLe...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Texas Biotechnology Corporation Curated by ChEMBL					Assay Description In vitro inhibition of HL60 (human leukemia) cell binding to human recombinant e-selectin.				J Med Chem 38: 4976-84 (1996) BindingDB Entry DOI: 10.7270/Q2B56KCP
Texas Biotechnology Corporation Curated by ChEMBL					More data for this Ligand-Target Pair
Leukocyte adhesion molecule-1 (Mus musculus)	BDBM50450369 (SIALYL LEWIS X \| Sialyl LeX \| Sialyl lewis-x \| sLe...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Texas Biotechnology Corporation Curated by ChEMBL					Assay Description In vitro inhibitory activity against sialyl Lewis X expressing HL60 cell binding Selectin L				J Med Chem 38: 4976-84 (1996) BindingDB Entry DOI: 10.7270/Q2B56KCP
Texas Biotechnology Corporation Curated by ChEMBL					More data for this Ligand-Target Pair
P-selectin/P-selectin glycoprotein ligand 1 (Homo sapiens (Human))	BDBM50450369 (SIALYL LEWIS X \| Sialyl LeX \| Sialyl lewis-x \| sLe...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Texas Biotechnology Corporation Curated by ChEMBL					Assay Description In vitro inhibitory activity against sialyl Lewis X expressing HL60 cell binding Selectin P				J Med Chem 38: 4976-84 (1996) BindingDB Entry DOI: 10.7270/Q2B56KCP
Texas Biotechnology Corporation Curated by ChEMBL					More data for this Ligand-Target Pair
Leukocyte adhesion molecule-1 (Homo sapiens (Human))	BDBM50450369 (SIALYL LEWIS X \| Sialyl LeX \| Sialyl lewis-x \| sLe...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
New Drug Research Laboratory Curated by ChEMBL					Assay Description Inhibitory concentration against blocking of Selectin L during migration of inflammatory cells to inflammatory site				J Med Chem 39: 2055-9 (1996) Article DOI: 10.1021/jm950877m BindingDB Entry DOI: 10.7270/Q2KH0P0B
New Drug Research Laboratory Curated by ChEMBL					More data for this Ligand-Target Pair
Selectin E (Homo sapiens (Human))	BDBM50450369 (SIALYL LEWIS X \| Sialyl LeX \| Sialyl lewis-x \| sLe...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
New Drug Research Laboratory Curated by ChEMBL					Assay Description Inhibitory concentration against blocking of E-selectin during migration of inflammatory cells to inflammatory site				J Med Chem 39: 2055-9 (1996) Article DOI: 10.1021/jm950877m BindingDB Entry DOI: 10.7270/Q2KH0P0B
New Drug Research Laboratory Curated by ChEMBL					More data for this Ligand-Target Pair
P-selectin/P-selectin glycoprotein ligand 1 (Homo sapiens (Human))	BDBM50450369 (SIALYL LEWIS X \| Sialyl LeX \| Sialyl lewis-x \| sLe...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
New Drug Research Laboratory Curated by ChEMBL					Assay Description Inhibitory concentration against blocking of Selectin P during migration of inflammatory cells to inflammatory site				J Med Chem 39: 2055-9 (1996) Article DOI: 10.1021/jm950877m BindingDB Entry DOI: 10.7270/Q2KH0P0B
New Drug Research Laboratory Curated by ChEMBL					More data for this Ligand-Target Pair
P-selectin/P-selectin glycoprotein ligand 1 (Homo sapiens (Human))	BDBM50450369 (SIALYL LEWIS X \| Sialyl LeX \| Sialyl lewis-x \| sLe...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against human chimeric Selectin P-Ig				J Med Chem 39: 1339-43 (1996) Article DOI: 10.1021/jm9506478 BindingDB Entry DOI: 10.7270/Q2513ZWW
					More data for this Ligand-Target Pair
Leukocyte adhesion molecule-1 (Homo sapiens (Human))	BDBM50450369 (SIALYL LEWIS X \| Sialyl LeX \| Sialyl lewis-x \| sLe...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against human chimeric L-selectin-Ig				J Med Chem 39: 1339-43 (1996) Article DOI: 10.1021/jm9506478 BindingDB Entry DOI: 10.7270/Q2513ZWW
					More data for this Ligand-Target Pair
Selectin E (Homo sapiens (Human))	BDBM50450369 (SIALYL LEWIS X \| Sialyl LeX \| Sialyl lewis-x \| sLe...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against human chimeric E-selectin-Ig				J Med Chem 39: 1339-43 (1996) Article DOI: 10.1021/jm9506478 BindingDB Entry DOI: 10.7270/Q2513ZWW
					More data for this Ligand-Target Pair
P-selectin (Mus musculus)	BDBM50450369 (SIALYL LEWIS X \| Sialyl LeX \| Sialyl lewis-x \| sLe...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Kanebo Curated by ChEMBL					Assay Description Blocking activity using seletin-IgG chimeras in a Selectin P competitive binding assay.				J Med Chem 40: 3534-41 (1997) Article DOI: 10.1021/jm970262k BindingDB Entry DOI: 10.7270/Q2NP253K
Kanebo Curated by ChEMBL					More data for this Ligand-Target Pair
Leukocyte adhesion molecule-1 (Mus musculus)	BDBM50450369 (SIALYL LEWIS X \| Sialyl LeX \| Sialyl lewis-x \| sLe...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Kanebo Curated by ChEMBL					Assay Description Blocking activity using seletin-IgG chimeras in a Selectin L competitive binding assay.				J Med Chem 40: 3534-41 (1997) Article DOI: 10.1021/jm970262k BindingDB Entry DOI: 10.7270/Q2NP253K
Kanebo Curated by ChEMBL					More data for this Ligand-Target Pair
Selectin E (Mus musculus)	BDBM50450369 (SIALYL LEWIS X \| Sialyl LeX \| Sialyl lewis-x \| sLe...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kanebo Curated by ChEMBL					Assay Description In vitro inhibitory activity against Selectin E-sialyl Lewis X (sLex) binding				J Med Chem 40: 3534-41 (1997) Article DOI: 10.1021/jm970262k BindingDB Entry DOI: 10.7270/Q2NP253K
Kanebo Curated by ChEMBL					More data for this Ligand-Target Pair
Leukocyte adhesion molecule-1 (Homo sapiens (Human))	BDBM50450369 (SIALYL LEWIS X \| Sialyl LeX \| Sialyl lewis-x \| sLe...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Kanebo Curated by ChEMBL					Assay Description Inhibition of Selectin L binding				J Med Chem 41: 4279-87 (1998) Article DOI: 10.1021/jm980267x BindingDB Entry DOI: 10.7270/Q2474BHN
Kanebo Curated by ChEMBL					More data for this Ligand-Target Pair
Selectin E (Homo sapiens (Human))	BDBM50450369 (SIALYL LEWIS X \| Sialyl LeX \| Sialyl lewis-x \| sLe...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kanebo Curated by ChEMBL					Assay Description Displacement of sialyl Lewis X (sLex) from selectin E				J Med Chem 41: 4279-87 (1998) Article DOI: 10.1021/jm980267x BindingDB Entry DOI: 10.7270/Q2474BHN
Kanebo Curated by ChEMBL					More data for this Ligand-Target Pair
P-selectin/P-selectin glycoprotein ligand 1 (Homo sapiens (Human))	BDBM50450369 (SIALYL LEWIS X \| Sialyl LeX \| Sialyl lewis-x \| sLe...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Kanebo Curated by ChEMBL					Assay Description Inhibition of Selectin P binding				J Med Chem 41: 4279-87 (1998) Article DOI: 10.1021/jm980267x BindingDB Entry DOI: 10.7270/Q2474BHN
Kanebo Curated by ChEMBL					More data for this Ligand-Target Pair
Leukocyte adhesion molecule-1 (Homo sapiens (Human))	BDBM50450369 (SIALYL LEWIS X \| Sialyl LeX \| Sialyl lewis-x \| sLe...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.50E+6	n/a	n/a	n/a	n/a	n/a	n/a
Texas Biotechnology Corporation Curated by ChEMBL					Assay Description Tested in vitro for the concentration to inhibit sLex bearing HL-60 cells binding to Selectin L-IgG fusion proteins				J Med Chem 41: 1099-111 (1998) Article DOI: 10.1021/jm9704917 BindingDB Entry DOI: 10.7270/Q2BP03G4
Texas Biotechnology Corporation Curated by ChEMBL					More data for this Ligand-Target Pair
Selectin E (Homo sapiens (Human))	BDBM50450369 (SIALYL LEWIS X \| Sialyl LeX \| Sialyl lewis-x \| sLe...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.30E+6	n/a	n/a	n/a	n/a	n/a	n/a
Texas Biotechnology Corporation Curated by ChEMBL					Assay Description Tested in vitro for the concentration to inhibit sLex bearing HL-60 cells binding to Selectin E-IgG fusion proteins by 50%.				J Med Chem 41: 1099-111 (1998) Article DOI: 10.1021/jm9704917 BindingDB Entry DOI: 10.7270/Q2BP03G4
Texas Biotechnology Corporation Curated by ChEMBL					More data for this Ligand-Target Pair
P-selectin/P-selectin glycoprotein ligand 1 (Homo sapiens (Human))	BDBM50450369 (SIALYL LEWIS X \| Sialyl LeX \| Sialyl lewis-x \| sLe...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.40E+6	n/a	n/a	n/a	n/a	n/a	n/a
Texas Biotechnology Corporation Curated by ChEMBL					Assay Description Tested in vitro for the concentration to inhibit sLex bearing HL-60 cells binding to Selectin P-IgG fusion proteins				J Med Chem 41: 1099-111 (1998) Article DOI: 10.1021/jm9704917 BindingDB Entry DOI: 10.7270/Q2BP03G4
Texas Biotechnology Corporation Curated by ChEMBL					More data for this Ligand-Target Pair
Selectin (Homo sapiens (Human))	BDBM50450369 (SIALYL LEWIS X \| Sialyl LeX \| Sialyl lewis-x \| sLe...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars		n/a	n/a	<1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of ET- 1 stimulated arachidonic acid release (AAR) in cultured rabbit renal vascular smooth muscle cells expressing the endothelin B recep...				Citation and Details BindingDB Entry DOI: 10.7270/Q28W3GG8
TBA					More data for this Ligand-Target Pair
Selectin (Homo sapiens (Human))	BDBM50450369 (SIALYL LEWIS X \| Sialyl LeX \| Sialyl lewis-x \| sLe...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	Article	n/a	n/a	3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit the binding to Selectin E immobilized on SPA beads of radiolabeled HL-60 cell membrane was determined				Bioorg Med Chem Lett 5: 2637-2642 (1995) Article DOI: 10.1016/0960-894X(95)00469-A BindingDB Entry DOI: 10.7270/Q25D8SBB
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Selectin (Homo sapiens (Human))	BDBM50450369 (SIALYL LEWIS X \| Sialyl LeX \| Sialyl lewis-x \| sLe...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Montr£al Curated by ChEMBL					Assay Description Concentration required to inhibit the interaction of Selectin E and HL-60 cells				Bioorg Med Chem Lett 11: 1109-12 (2001) BindingDB Entry DOI: 10.7270/Q28C9WSC
Universit£ de Montr£al Curated by ChEMBL					More data for this Ligand-Target Pair
Selectin (Homo sapiens (Human))	BDBM50450369 (SIALYL LEWIS X \| Sialyl LeX \| Sialyl lewis-x \| sLe...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Montr£al Curated by ChEMBL					Assay Description Concentration required to inhibit the interaction of Selectin E and HL-60 cells				Bioorg Med Chem Lett 11: 1109-12 (2001) BindingDB Entry DOI: 10.7270/Q28C9WSC
Universit£ de Montr£al Curated by ChEMBL					More data for this Ligand-Target Pair
P-selectin/P-selectin glycoprotein ligand 1 (Homo sapiens (Human))	BDBM50450369 (SIALYL LEWIS X \| Sialyl LeX \| Sialyl lewis-x \| sLe...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.50E+6	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Montr£al Curated by ChEMBL					Assay Description Concentration required to inhibit the interaction of Selectin P and HL-60 cells				Bioorg Med Chem Lett 11: 1109-12 (2001) BindingDB Entry DOI: 10.7270/Q28C9WSC
Universit£ de Montr£al Curated by ChEMBL					More data for this Ligand-Target Pair
Selectin E (Homo sapiens (Human))	BDBM50450369 (SIALYL LEWIS X \| Sialyl LeX \| Sialyl lewis-x \| sLe...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Nippon Organon K.K. Curated by ChEMBL					Assay Description In vitro inhibitory activity of compound was determined against Selectin E binding by ELISA assay				Bioorg Med Chem Lett 10: 1827-30 (2000) BindingDB Entry DOI: 10.7270/Q2ZP46M8
Nippon Organon K.K. Curated by ChEMBL					More data for this Ligand-Target Pair