BDBM50450656 CHEMBL2114469
SMILES: CC(C)C[C@@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)CNC(=O)[C@]1(CCC[C@@H]1O)NC(=O)[C@H](N)Cc1ccc(O)cc1)C(O)=O
InChI Key: InChIKey=NFIKZROQWRUGJB-MEBNVULWSA-N
Data: 4 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Opioid receptors; mu & delta (Rattus norvegicus (rat)) | BDBM50450656 (CHEMBL2114469) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.0400 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Bioorganic Research Curated by ChEMBL | Assay Description Binding affinity against rat Opioid receptor delta 1 expressed in CHO cells determined by competitive inhibition of 1 nM [3H]DPDPE. | Bioorg Med Chem Lett 8: 2027-32 (1999) BindingDB Entry DOI: 10.7270/Q25T3KZ5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Opioid receptors; mu & delta (Rattus norvegicus (rat)) | BDBM50450656 (CHEMBL2114469) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.0100 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Bioorganic Research Curated by ChEMBL | Assay Description Inhibitory activity against forskolin-stimulated cAMP production in chinese hamster ovary cells expressing Opioid receptor delta 1 | Bioorg Med Chem Lett 8: 2027-32 (1999) BindingDB Entry DOI: 10.7270/Q25T3KZ5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Rattus norvegicus (rat)) | BDBM50450656 (CHEMBL2114469) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Bioorganic Research Curated by ChEMBL | Assay Description Binding affinity against rat kappa-opioid receptor expressed in CHO cells was determined by competitive inhibition of 2 nM [3H]-U 69593 | Bioorg Med Chem Lett 8: 2027-32 (1999) BindingDB Entry DOI: 10.7270/Q25T3KZ5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Rattus norvegicus (rat)) | BDBM50450656 (CHEMBL2114469) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Bioorganic Research Curated by ChEMBL | Assay Description Binding affinity against rat mu-opioid receptor expressed in CHO cells by competitive inhibition of 1 nM [3H]DAMGO | Bioorg Med Chem Lett 8: 2027-32 (1999) BindingDB Entry DOI: 10.7270/Q25T3KZ5 | |||||||||||
More data for this Ligand-Target Pair |