null

SMILES: O\C(=C/C(=O)C1CCN(Cc2ccccc2)CC1)c1ccc(Cl)cc1

InChI Key: InChIKey=IALFUNSVFHBTHD-ZHZULCJRSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50454602   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50454602 (CHEMBL2112285) Show SMILES O\C(=C/C(=O)C1CCN(Cc2ccccc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H22ClNO2/c22-19-8-6-17(7-9-19)20(24)14-21(25)18-10-12-23(13-11-18)15-16-4-2-1-3-5-16/h1-9,14,18,24H,10-13,15H2/b20-14-	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Curated by ChEMBL					Assay Description Ability to displace [3H]-spiperone from human dopamine receptor D4 (hD4) receptor stably expressed in HEK-293 cells.				J Med Chem 40: 2374-85 (1997) Article DOI: 10.1021/jm970111h BindingDB Entry DOI: 10.7270/Q2PN94R9
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50454602 (CHEMBL2112285) Show SMILES O\C(=C/C(=O)C1CCN(Cc2ccccc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H22ClNO2/c22-19-8-6-17(7-9-19)20(24)14-21(25)18-10-12-23(13-11-18)15-16-4-2-1-3-5-16/h1-9,14,18,24H,10-13,15H2/b20-14-	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Curated by ChEMBL					Assay Description Ability to displace [3H]-spiperone from human dopamine receptor D2 stably expressed in CHO cells.				J Med Chem 40: 2374-85 (1997) Article DOI: 10.1021/jm970111h BindingDB Entry DOI: 10.7270/Q2PN94R9
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50454602 (CHEMBL2112285) Show SMILES O\C(=C/C(=O)C1CCN(Cc2ccccc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H22ClNO2/c22-19-8-6-17(7-9-19)20(24)14-21(25)18-10-12-23(13-11-18)15-16-4-2-1-3-5-16/h1-9,14,18,24H,10-13,15H2/b20-14-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	510	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Curated by ChEMBL					Assay Description Ability to displace [3H]-spiperone from human dopamine receptor D3 (hD3) receptor stably expressed in HEK-293 cells.				J Med Chem 40: 2374-85 (1997) Article DOI: 10.1021/jm970111h BindingDB Entry DOI: 10.7270/Q2PN94R9
					More data for this Ligand-Target Pair