null
SMILES: [H][C@]12CC[C@]([H])(C[C@@H](C1)OC(c1ccccc1)c1ccccc1F)N2C
InChI Key: InChIKey=FLMFVONYZLSMMT-TWYXQDJOSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Muscarinic acetylcholine receptor M1 (RAT) | BDBM50454830 (CHEMBL3084869) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.430 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institutes of Health Curated by ChEMBL | Assay Description Displacement of [3H]pirenzepine binding at muscarinic Muscarinic acetylcholine receptor M1 in rat brain P2 membranes. | J Med Chem 40: 851-7 (1997) Article DOI: 10.1021/jm950782k BindingDB Entry DOI: 10.7270/Q21R6R54 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50454830 (CHEMBL3084869) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 50 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institutes of Health Curated by ChEMBL | Assay Description Displacement of [3H]WIN-35428 binding to the dopamine transporter (DAT) in Rat Caudate Putamen | J Med Chem 40: 851-7 (1997) Article DOI: 10.1021/jm950782k BindingDB Entry DOI: 10.7270/Q21R6R54 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50454830 (CHEMBL3084869) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 50 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL | Assay Description Binding affinity to dopamine transporter (DAT) using [3H]WIN-35428 as a radioligand | J Med Chem 43: 4151-9 (2000) Article DOI: 10.1021/jm990472s BindingDB Entry DOI: 10.7270/Q2PK0JWZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50454830 (CHEMBL3084869) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institutes of Health Curated by ChEMBL | Assay Description [3H]-Dopamine uptake inhibition in rat caudate putamen | J Med Chem 40: 851-7 (1997) Article DOI: 10.1021/jm950782k BindingDB Entry DOI: 10.7270/Q21R6R54 | |||||||||||
More data for this Ligand-Target Pair |